Potential Risks and Factors of Women’s Health Promotion

Costantino, Claudio; Casuccio, Alessandra; Restivo, Vincenzo

doi:10.3390/ijerph17249555

Cited by 1 publication

(1 citation statement)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Despite numerous studies, the pathomechanism of dysmenorrhea is not fully understood. Previous studies have shown that dysmenorrhea is a complex process that may depend on many factors [1][2][3][4]. It is known that susceptibility to dysmenorrhea may be associated with genetic factors with the elevated secretion of prostaglandins and hormones such as estrogen and progesterone [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

The evaluation of progesterone and dysmenorrhea levels after the manual therapy in young women in relation to the use of non-steroidal anti-inflammatory drugs

Barcikowska

Grzybowska

Rajkowska-Labon

et al. 2021

Proceedings of the 3rd International Electronic Conference on Environmental Research and Public Health —Public Health Issues In

View full text Add to dashboard Cite

Introduction: In spite of many studies, the pathomechanism of dysmenorrhea (DM) remains unclear. The study aimed to evaluate the levels of progesterone and 17-beta estradiol and the severity of dysmenorrhea in six young women, including three after the use of manual therapy and the other three after the administration of ibuprofen. Material and methods: In six patients aged 22±2, gynecological and physiotherapeutic examinations were completed. Moreover, a two-fold determination of progesterone and 17-beta estradiol levels were carried out. The intensity of dysmenorrhea was assessed in the numerical pain rating scale (NPRS). The patients were dichotomized into two subgroups. Subgroup A (n=3) was subjected to manual therapy (3 x 45 min), while in subgroup B (n=3), the patients were administered ibuprofen 3 x 400 mg/24 h during menstruation. Results: Lower progesterone levels were detected in the blood of the 3 women from subgroup A after manual therapy and in 2 of the women from subgroup B after administrating ibuprofen. After the therapy, the level of 17-beta estradiol was higher in each woman from subgroup A and in one woman from subgroup B. In subgroup A, dysmenorrhea was reduced on average from 8 down to 3 points in the NPRS and duration time was shortened by one day on average. In subgroup B, dysmenorrhea was decreased on average from 8 to 3 points in the NPRS, yet no changes in its duration time were observed. Conclusions: It has been demonstrated that manual therapy alleviated dysmenorrhea to a similar degree as ibuprofen. However, only the manual therapy exerted an effect on the shortening of dysmenorrhea duration time. The use of manual therapy probably influenced the diminution of progesterone levels.

show abstract