Potential relevance of salivary legumain for the clinical diagnostic of hand, foot, and mouth disease
Yong Wah Tan,
Fiona Mei Shan Teo,
Siok Ghee Ler
et al.
Abstract:The fight against hand, foot, and mouth disease (HFMD) remains an arduous challenge without existing point‐of‐care (POC) diagnostic platforms for accurate diagnosis and prompt case quarantine. Hence, the purpose of this salivary biomarker discovery study is to set the fundamentals for the realization of POC diagnostics for HFMD. Whole salivary proteome profiling was performed on the saliva obtained from children with HFMD and healthy children, using a reductive dimethylation chemical labeling method coupled wi… Show more
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