Potential Protectivity of a Conjugated COVID-19 Vaccine against Tetanus
Delaram Doroud,
Fatemeh Ashrafian,
Amir Javadi
et al.
Abstract:PastoCovac is a subunit protein vaccine against COVID-19 which contains the tetanus toxoid as a carrier conjugated to SARS-CoV-2 RBD. The primary goal of the tetanus application was to elicit a stronger specific response in the individuals. However, conjugate vaccines have the potency to generate anticarrier antibodies in addition to the target antigen. Therefore, the present study aimed to evaluate the PastoCovac vaccine in the humoral immune induction against tetanus. Six groups of individuals, including tho… Show more
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