Potential possibilities of bioengineering technologies and cellular implantation in hernioendoprosthetics (review article)

Abstract

The aim of this review is to determine the most effective way to improve hernioplasty in accordance with the literature data. Materials and methods. The scientific literature was analyzed using PubMed, Scopus, RINC, and Mendeley abstracting software. The review presents data reflecting the trends in the field under consideration over the last decade, according to the authors' opinion. Results. The use of cellular technologies can confirm the position of absorbable hernioprostheses by improving the quality of connective tissue of the postoperative scar and reducing the likelihood of postoperative complications. In the practice of wound treatment, collagen preparations and native fibroblasts are used, the use of which has positive data indicating a high potential of this type of therapy. The application of cell technologies could confirm the position of resorbable hernioprostheses by improving the quality of connective tissue of the postoperative scar and reducing the possibility of postoperative complications. Conclusion. Cellular implantation during hernioendoprosthetics is one of the most promising ways to solve the problem of preventive treatment of postoperative hernias of the anterior abdominal wall. The use of fibroblasts to enhance proliferative activity in the surgical wound will improve the quality characteristics of connective tissue and provide a more favorable long-term effect of the intervention, as well as prevent recurrence of hernias.