Potential plant-derived catecholaminergic activity enhancers for neuropharmacological approaches: A review

Neuroprotective activity of Indonesian traditional herbal medicine: A systematic review

“…Previous studies have reported that the successful application of R. graveolens in an in vivo murine DA model as an acetylcholinesterase (AChE) inhibitor (Colucci-D'Amato and Cimaglia, 2020) and BuChE inhibitor is the hexane extract of R. graveolens at a concentration of 400 g/ml. This extract had a dose-dependent inhibitory activity, and inhibition was higher than 50% at a concentration of 100 g/ml, the lowest concentration used (Bhattacharjee and Perumal, 2019;Coimbra et al, 2020). RT has demonstrated neuroprotective properties against brain ischemia.…”

“…Moreover, some are especially significant because they can interfere with pathogenic pathways implicated in neurodegenerative mechanisms' start and/or progression, such as those in PD, AD, and HD. Ruta graveolens inhibits monoamine oxidase B (MAO-B) in PD, according to research examining the plant's impact on neurodegenerative disorders (Bhattacharjee and Perumal, 2019;Coimbra et al, 2020).…”

Myricitrin – a flavonoid isolated from the Indian olive tree (Elaeocarpus floribundus) – inhibits Monoamine oxidase in the brain and elevates striatal dopamine levels: therapeutic implications against Parkinson's disease

“…On top of that, being polyphenolic, they have the potential to combat oxidative stress as well, which is one of the key physiological conditions for the progression of neurological disorders. 8,10 Several studies in the past have evaluated flavonoids against MAO activity and suggested that an increase in -OH groups in flavonoid structures led to decreased activity. Substitution on the A ring with a sugar moiety can also decrease the activity, whereas a p-OH substituted phenyl at C-2 and unsaturation at C2-C3 are favorable for the activity.…”

Optimization of extraction of Chaenomeles lagenaria polysaccharide and its antibacterial activity

“…As a medicinal and food homologous plant, C. lagenaria is rich in nutrients, such as polysaccharides, organic acids, pectin, protein, nitrogen acids, vitamins, minerals, steroids, flavonoids, triterpenes, and other active substances. It displays biological activities, such as bacteriostasis, antioxidant qualities, immune regulation, and cancer prevention; thus, it has a high medical value and broad market application prospects (Parikh et al 2014;Bhattacharjee and Perumal 2019;Suroowan et al 2019). However, at present, there are few reports on the extraction of polysaccharides from Chaenomeles lagenaria.…”