Potential of Red Fruit Oil as an Ointment for Burns on Rabbits (Oryctolagus cuniculus)

Abstract

Herbal medicine in Indonesia is often used as a healing medium. Red fruit as one of the endemic medicinal plants in Papua has a high content of various active ingredients and antioxidants so it can treat various diseases. The use of topical medicinal preparations in the form of ointments for the treatment of burns is considered the easiest to apply to livestock. The antioxidant content in red fruit accelerates the regeneration of dead skin cells so it is hoped that it can be used as a topical treatment for burns. Antioxidant therapy for burn management has been widely researched. This study aims to determine the quality and effectiveness of red fruit oil herbal from Papua in the ointment preparations for healing burns in rabbits (Oryctolagus cuniculus). This study used a completely randomized design (CRD) which consisted of 4 treatments. The treatment given was P0 = Vaseline without red fruit oil (negative control); P1 = Red fruit oil ointment 15%; P2 = Red fruit oil ointment 30%; P3 = Red fruit oil ointment 45%. Variables to be measured and observed in this study include the stability of the ointment preparation (organoleptic test, homogeneity test, spreadability test, ointment pH test, and freeze-thaw cycle stability test and the effectiveness of red fruit oil ointment against burns in rabbits. The quality of red fruit oil ointment for the treatment of burns in rabbits (Oryctolagus cuniculus) was the best in the P3 formulation (45% red fruit oil) but in the spreadability test, it was still relatively low.