This paper seeks to illustrate differentiated access and transport constraints faced by public transport commuters in Gauteng province, South Africa. Drawing from a one thousand five hundred and fifty (1550) randomized household sample conducted in Gauteng province, South Africa, different access strokes and constraints are discussed. In any case, these findings are benchmarked and analysed in the context of the national household travel survey (NHTS) 2013 findings that was conducted by the Department of Transport (DoT). The major findings highlight differentiated commuting access and transport constraints in Gauteng province. The analysis highlights the existing of differentiated access and transport constraints for public transport commuters in Gauteng province. The driving group has to deal with problems of traffic congestion, road rage, travelling time and travel delay among other issues. The public transport group in addition to long commuting distances, travelling times has to deal with low service levels, off-peak infrequent to non-existing service, crime as well as challenges associated with non-scheduled transport systems. There is therefore, differentiated access and transport problems for public transport users who make use of the three main different modes, namely train, bus and minibus taxis. Implementing a raft of integrated, smart, transit orientated development (ToD), appropriate land use, public transport policy and action measures has potential to relieve the different transport access strokes and constraints in the study area.