“…In the last decade, dietary components have shown the ability to reduce the toxicity of environmental pollutants, and a rising body of scientific evidence indicates that phytoantioxidants, particularly flavonoids, play a part in preventing or reducing the damage caused by HMs, owing to their antioxidant and metal-chelating properties [2]. Phytochemicals were shown to mitigate HM-mediated toxicity [32], specifically from As [33,34], arsenic trioxide [35], Cd and Pb [36]. Many flavonoids, such as gossypin (3,5,8,3 ′ ,4 ′ -pentahydroxy-7-O-glucosyl flavone, originally isolated from Hibiscus vitifolius) and quercetin have recently gained attention for their potential role in reducing the accumulation of HMs in biological systems [30].…”