Potential of medicinal plants from the Brazilian semi-arid region (Caatinga) against Staphylococcus epidermidis planktonic and biofilm lifestyles

Trentin, Danielle da Silva; Giordani, Raquel Brandt; Zimmer, Karine Rigon; Silva, Alexandre Gomes da; Silva, Márcia Vanusa da; Correia, Maria Tereza dos Santos; Baumvol, Israel Jacob Rabin; Macêdo, Alexandre José

doi:10.1016/j.jep.2011.05.030

Cited by 160 publications

(96 citation statements)

References 28 publications

(34 reference statements)

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“…For each well a difference was calculated (T24b -T0 or T48b-T0). To relate the results of the potential inhibitors to the negative (untreated) control, the latter was considered as 100% biofilm formation and a percentage value for each extract and EDTA was calculated (Trentin et al 2011). Any value lower than 100% was considered inhibition or eradication of biofilm.…”

Section: Discussionmentioning

confidence: 99%

Antibiofilm effect of Tucum (Astrocaryum sp.) endosperm against Candida albicans

Melo¹,

Santos²,

Velozo³

et al. 2016

Afr. J. Microbiol. Res.

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Candida albicans is one of the most relevant human opportunistic pathogens and highly competent to build biofilms on vital and non-vital surfaces. Facing the escalating resistance of microorganisms to current antimicrobials and fungicides, the Amazonian biodiversity may bring raw material to the development of new antimicrobial drugs. Astrocaryum sp. is a regional fruit, consumed in natura or as ice creams and other local specialties. The seeds, however, are discarded and accumulate in the environment. The present study aimed to characterize the phytochemical composition of the endosperm and to evaluate the effect of its extracts on biofilm formation and eradication by C. albicans. The seeds were processed to obtain extracts in hexane and ethanol. Color chromatography procedure and thin layer chromatography were used, followed by a colorimetric phytochemical prospection to identify the major secondary metabolites. Microtiter plates were inoculated with C. albicans and incubated for 24 h in contact with the extracts or EDTA (positive control) to test the ability of preventing biofilm formation. To evaluate the biofilm eradication effect, the target strain was inoculated in the plates and incubated for 24 h previously to the addition of the extracts or EDTA. Both hexane and ethanol extracts demonstrated significantly higher effect than EDTA on Candida biofilm inhibition, highlighting hexane extract that achieved the lowest percentage of adhesion (9.46±0.9%). The chemical composition indicated mainly terpenes, phenols and antioxidant compounds. These results demonstrate a pharmaceutical potential of Astrocaryum sp. endosperm for future developments of antifungal drugs, thus contributing to reduce the environmental impact of this biological waste of Amazonia.

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Section: Discussionmentioning

confidence: 99%

Antibiofilm effect of Tucum (Astrocaryum sp.) endosperm against Candida albicans

Melo¹,

Santos²,

Velozo³

et al. 2016

Afr. J. Microbiol. Res.

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“…Extensive studies of the anti-Staphylococcus epidermidis bio�lm activity of 45 aqueous extracts were published by Trentin et al [76] At 4 mg/mL, the most effective were extracts derived from Bauhinia acuruana branches (orchid tree), Chamaecrista desvauxii fruits, B. acuruana fruits, and Pityrocarpa moniliformis leaves, which decreased bio�lm formation by 81.7%, 87.4%, 77.8%, and 77%, respectively. When applied at 10-fold lower concentration, noteworthy bio�lm inhibition was observed only in the presence of Commiphora leptophloeos stem bark (corkwood) and Senna macranthera fruit extracts (reductions of 67.3% and 66.7%, resp.)…”

Section: Plant Extractsmentioning

confidence: 99%

“…When applied at 10-fold lower concentration, noteworthy bio�lm inhibition was observed only in the presence of Commiphora leptophloeos stem bark (corkwood) and Senna macranthera fruit extracts (reductions of 67.3% and 66.7%, resp.) [76].…”

Section: Plant Extractsmentioning

confidence: 99%

Antimicrobial, Antimycobacterial and Antibiofi lm Properties of Couroupita guianensis Aubl. Fruit Extract

Sayen¹

2014

Biofilm Control and Antimicrobial Agents

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We review the recent literature concerning the efficiency of antimicrobial photodynamic inactivation toward various microbial species in planktonic and bio�lm cultures. e review is mainly focused on bio�lm-growing microrganisms because this form of growth poses a threat to chronically infected or immunocompromised patients and is difficult to eradicate from medical devices. We discuss the bio�lm formation process and mechanisms of its increased resistance to various antimicrobials. We present, based on data in the literature, strategies for overcoming the problem of bio�lm resistance. �actors that have potential for use in increasing the efficiency of the killing of bio�lm-forming bacteria include plant extracts, enzymes that disturb the bio�lm structure, and other nonenzymatic molecules. We propose combining antimicrobial photodynamic therapy with various antimicrobial and antibio�lm approaches to obtain a synergistic effect to permit efficient microbial growth control at low photosensitizer doses.

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“…Screening is reported for quorum sensing-disrupting in dietary plant (food or seasoning plant) (Vattem et al, 2007), in which all species were active. Taking into account ethnobotanic criteria, a quorum sensing-disrupting and antibiofilm effects of plants from Florida, USA, and Caatinga plants from Brazil, respectively, were screened (Adonizio et al, 2006;Trentin et al, 2011).…”

Section: Plantmentioning

confidence: 99%

Antiadhesive Effect of Plant Compounds in Bacteria

Guirado¹,

Barreto²

2012

Phytochemicals as Nutraceuticals - Global Approaches to Their Role in Nutrition and Health

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Potential of medicinal plants from the Brazilian semi-arid region (Caatinga) against Staphylococcus epidermidis planktonic and biofilm lifestyles

Cited by 160 publications

References 28 publications

Antibiofilm effect of Tucum (Astrocaryum sp.) endosperm against Candida albicans

Antibiofilm effect of Tucum (Astrocaryum sp.) endosperm against Candida albicans

Antimicrobial, Antimycobacterial and Antibiofi lm Properties of Couroupita guianensis Aubl. Fruit Extract

Antiadhesive Effect of Plant Compounds in Bacteria

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