DOI: 10.1096/fasebj.2020.34.s1.06440
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Potential of Aerobic Physical Training to Minimize the Effects of Leptin Deficiency in Female Mice

Abstract: Aerobic physical training (APT) is an important strategy for prevention and treatment of comorbidities such as type 2 diabetes and obesity. Leptin and adiponectin play an important role in energy metabolism, whose imbalance is strongly related to obesity and insulin resistance (IR). Although women have higher levels of leptin and adiponectin compared to men, in conditions such as obesity and/or type 2 diabetes these levels decrease, abolishing the protective effects of these adipokines in females. This study i… Show more

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