Potential Neuroprotective Activity of Essential Oils in Memory and Learning Impairment

Silva-Correa, Carmen R.; Campos-Reyna, Jorge L.; Torre, Víctor E. Villarreal-La; Calderón-Peña, Abhel A.; Sagástegui-Guarniz, William Antonio; Guerrero-Espino, Luz M.; González-Siccha, Anabel D.; Aspajo-Villalaz, Cinthya L.; González-Blas, María V.; Cruzado-Razco, José L.; Hilario-Vargas, Julio

doi:10.5530/pj.2021.13.166

Cited by 4 publications

(3 citation statements)

References 88 publications

(108 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Memory-enhancing properties have also been reported for some of the studied monoterpenes [58]. For example, thymol's positive effect on cognitive deficits, associated with a high-fat diet in mice, was found by Fang et al (2017) [59].…”

Section: Introductionmentioning

confidence: 76%

Therapeutic Potential of Myrtenal and Its Derivatives—A Review

Dragomanova,

Andonova,

Volcho

et al. 2023

Life

View full text Add to dashboard Cite

The investigation of monoterpenes as natural products has gained significant attention in the search for new pharmacological agents due to their ability to exhibit a wide range in biological activities, including antifungal, antibacterial, antioxidant, anticancer, antispasmodic, hypotensive, and vasodilating properties. In vitro and in vivo studies reveal their antidepressant, anxiolytic, and memory-enhancing effects in experimental dementia and Parkinson’s disease. Chemical modification of natural substances by conjugation with various synthetic components is a modern method of obtaining new biologically active compounds. The discovery of new potential drugs among monoterpene derivatives is a progressive avenue within experimental pharmacology, offering a promising approach for the therapy of diverse pathological conditions. Biologically active substances such as monoterpenes, for example, borneol, camphor, geraniol, pinene, and thymol, are used to synthesize compounds with analgesic, anti-inflammatory, anticonvulsive, antidepressant, anti-Alzheimer’s, antiparkinsonian, antiviral and antibacterial (antituberculosis) properties. Myrtenal is a perspective monoterpenoid with therapeutic potential in various fields of medicine. Its chemical modifications often lead to new or more pronounced biological effects. As an example, the conjugation of myrtenal with the established pharmacophore adamantane enables the augmentation of several of its pivotal properties. Myrtenal–adamantane derivatives exhibited a variety of beneficial characteristics, such as antimicrobial, antifungal, antiviral, anticancer, anxiolytic, and neuroprotective properties, which are worth examining in more detail and at length.

show abstract

Section: Introductionmentioning

confidence: 76%

Therapeutic Potential of Myrtenal and Its Derivatives—A Review

Dragomanova,

Andonova,

Volcho

et al. 2023

Life

View full text Add to dashboard Cite

show abstract

“…In addition, natural products have played an essential role in the discovery of analgesic drugs, due to the frequent adverse effects associated with pain therapy, which have driven the search for new antinociceptive compounds [102] . However, data on the antinociceptive effect of products derived from stingless bees are still limited.…”

Section: Resultsmentioning

confidence: 99%

Chemical Profile and Biological Potential of Scaptotrigona Bee Products (Hymenoptera, Apidae, Meliponini): An Review

de Sousa Silveira,

Silva Macêdo,

de Menezes Dantas

et al. 2024

Chemistry & Biodiversity

View full text Add to dashboard Cite

Stingless bees belong to the Meliponini tribe and are widely distributed in the tropics and subtropics, where they perform important ecological services. Among the best distributed groups of stingless bees is the genus Scaptotrigona, which includes 22 species distributed throughout the neotropical region, including the area from Mexico to Argentina. Bees of this genus are responsible for the production of products such as honey, propolis, geopropolis and fermented pollen (“saburá”). This review aimed to provide an overview of the chemical composition and biological activities associated with derived products from stingless bees of the genus Scaptotrigona. The bibliographic review was carried out through searches in the Scopus, Web of Science, ScienceDirect and PubMed databases, including publications from 2003 to January 2023. The study of the chemodiversity of products derived from Scaptotrigona demonstrated the mainly presence of flavonoids, phenolic acids, terpenoids and alkaloids. It was also demonstrated that products derived from bees of the genus Scaptotrigona exhibit a wide range of biological effects, such as antibacterial, antioxidant, anti‐inflammatory and antifungal activities, among other bioactivities. This review provides an overview of phytochemical and pharmacological investigations of the genus Scaptotrigona. However, it is essential to clarify the toxicity and food safety of these products.

show abstract

“…• Neurological Effects and Mood Regulation: Scientific interest in essential oils' impact on the nervous system has surged, with investigations into their potential to alleviate stress, anxiety, and depression. Certain oils, like bergamot and frankincense, have shown modulating effects on neurotransmitters, shedding light on their potential role in mental well-being [10,11].…”

Section: Overview Of Recent Scientific Studies and Breakthroughsmentioning

confidence: 99%

Essential Oils and Their Bioactive Molecules: Recent Advances and New Applications

Mkaddem Mounira

2024

Biochemistry

View full text Add to dashboard Cite

This chapter explores the latest advancements and applications of essential oils, focusing on evidence-based research and practical insights. Beginning with an introduction to essential oils’ historical significance, it outlines recent breakthroughs in research, novel extraction techniques, and advancements in understanding their chemical composition. New perspectives on essential oil use are explored, including their potential to promote mental well-being, applications in environmental practices, and emerging industry trends. The chapter highlights innovative applications, such as aromatherapy, skincare, and culinary arts. In healthcare, evidence-based applications and research on antimicrobial properties and pain management are discussed. Real-world case studies demonstrate essential oils’ impact across various industries. The chapter also addresses challenges, including safety, ethics, and regulatory considerations. Future research opportunities are identified, emphasizing essential oils’ potential in cutting-edge fields like nanotechnology and biomedicine. In conclusion, essential oils offer a rich source of health and innovation, bridging traditional knowledge with modern advancements. Their significance in diverse applications invites further exploration and utilization to unlock their full potential.

show abstract

Potential Neuroprotective Activity of Essential Oils in Memory and Learning Impairment

Cited by 4 publications

References 88 publications

Therapeutic Potential of Myrtenal and Its Derivatives—A Review

Therapeutic Potential of Myrtenal and Its Derivatives—A Review

Chemical Profile and Biological Potential of Scaptotrigona Bee Products (Hymenoptera, Apidae, Meliponini): An Review

Essential Oils and Their Bioactive Molecules: Recent Advances and New Applications

Contact Info

Product

Resources

About