Potential Modulation of Disease Activity Indices and Inflammatory Biomarkers in Patients With Active Inflammatory Bowel Disease on Melatonin Adjuvant Therapy
Abstract:Objective: The objective of this study was to explore the benefits of melatonin supplementation in the active stage of moderate to severe inflammatory bowel diseases (IBDs) as an adjuvant to the standard immunosuppressant and biological targeting therapy in both Crohn's disease (CD) and ulcerative colitis (UC) patients.Methods: This is an interventional prospective randomized controlled, open-label, single-center study was carried out on 50 patients visiting the inpatient biology unite diagnosed as moderate-se… Show more
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