“…Intense sweetener intake has been widely studied in both the diabetic and general populations (Virtanen et al, 1988;Heybach & Ross, 1989;MAFF, 1990;Bär & Bierman, 1992;Hinson & Nicol, 1992;Hulshof & Bouman, 1992;Bergsten, 1993;CRÉ DOC, 1994;MAFF, 1995;Toledo & Ioshi, 1995;Elmadfa et al, 1996;Ishiwata et al, 1998;Leclerq et al, 1999;Renwick, 1999). There is no evidence in any of these studies that individuals exceed the Acceptable Daily Intake (ADI) of one or more intense sweeteners on a long-term basis.…”