Potential Impact of Time Trend of Lifestyle Risk Factors on Burden of Major Gastrointestinal Cancers in China

Wu, You; Li, Yanping; Giovannucci, Edward

doi:10.1053/j.gastro.2021.08.006

Cited by 51 publications

(49 citation statements)

References 66 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A low-risk lifestyle can reduce GI cancer risk by as much as 50% [6]. Therefore, we should pursue a healthy lifestyle that includes following a prudent diet and avoid-ing excess body weight, pursuing an active exercise program, minimizing alcohol intake, and refraining from smoking tobacco.…”

Section: Preventive Oncologymentioning

confidence: 99%

See 1 more Smart Citation

Tobacco Smoking and Gastrointestinal Cancer Risk

Scherübl¹

2022

Visc Med

View full text Add to dashboard Cite

Background: Smoking tobacco is the most preventable cause of gastrointestinal (GI) cancer disease in Germany. The more and the longer you smoke, the higher your risk of GI cancer. About 28% of 18–64 year-old Germans are current smokers; in addition, 11% of the population is regularly exposed to secondhand tobacco smoke. Summary: Tobacco use is causally associated with esophageal, gastric, pancreatic, biliary, hepatocellular, colorectal, and anal cancers. Combining smoking with alcohol use, excess body weight, diabetes, or chronic infections synergistically enhances GI cancer risk. Smoking cessation effectively reduces tobacco-associated GI cancer risk. Key Messages: Smokers should be encouraged to stop smoking tobacco and join programs of risk-adaptive cancer screening.

show abstract

Section: Preventive Oncologymentioning

confidence: 99%

“…A low-risk lifestyle can reduce overall gastrointestinal (GI) cancer risk by about 50% [6]. Stopping the use of tobacco yields remarkable health benefits.…”

Section: Introductionmentioning

confidence: 99%

Tobacco Smoking and Gastrointestinal Cancer Risk

Scherübl¹

2022

Visc Med

View full text Add to dashboard Cite

show abstract

“…Bewegungsmangel, übermäßiges Körpergewicht (BMI ≥ 25,0 kg/m 2 ) und eine unausgewogene Ernährung sind wichtige und beeinflussbare Risikofaktoren von gastrointestinalen Adenokarzinomen [10,25,26,27,28], zugleich stellen sie die häufigste Ursache von Typ-2-Diabetes mellitus (T2D) dar. Große Besorgnis erregt die signifikante Inzidenzzunahme von T2D bei Kindern und Heranwachsenden und es erkranken nun immer mehr junge Erwachsene (< 50 Jahre) an T2D-assoziierten, gastrointestinalen Adenokarzinomen [10,12,26,29] (▶ Abb.…”

Section: Einführungunclassified

Typ-2-Diabetes mellitus und gastrointestinale Krebsvorsorge

Scherübl

2022

Z Gastroenterol

View full text Add to dashboard Cite

ZusammenfassungIn Deutschland sind mehr als 8 Millionen Menschen diabeteskrank. Patienten mit Typ-2-Diabetes mellitus (T2D) haben ein erhöhtes Risiko für gastrointestinale Adenokarzinome, sie erkranken z.T. früher und weisen i.d.R. ein ungünstigeres, tumorspezifisches 5-Jahres-Überleben auf als Stoffwechselgesunde. Krebs ist nun die Haupttodesursache von Menschen mit T2D. Die chronische Hyperglykämie und die Insulinresistenz können das Wachstum von gastrointestinalen Tumoren begünstigen. So kann T2D Adenokarzinome des Dickdarms, der Bauchspeicheldrüse, der Gallenblase, der Gallengänge, der Leber, des Magens und der Speiseröhre verursachen. Ein gesunder Lebensstil und die Teilnahme an Vorsorgeuntersuchungen sind wichtig und können das tumorbedingte Erkrankungs- und Sterberisiko von T2D-Patienten erheblich verringern.

show abstract

“…Epidemiological evidence indicated the occurrence and development of digestive tract cancers are related to smoking, alcohol drinking, unhealthy diet, obesity, physical inactivity, virus infection, and others [4][5][6][7]. Shanghai is the largest metropolis, with ongoing changes in lifestyle and diet, diverse cultures, and a prosperous economy in China.…”

Section: Introductionmentioning

confidence: 99%

Incidence, Mortality Features and Lifetime Risk Estimation of Digestive Tract Cancers in an Urban District of Shanghai, China

Yuan

Jiang

et al. 2022

J Epidemiol Glob Health

View full text Add to dashboard Cite

Digestive tract cancers are the common cause of cancer deaths in both China and worldwide. This study aimed to describe the burden, recent trends and lifetime risks in the incidence and mortality of digestive tract cancers in an urban district of Shanghai, China. Our study extracted data on stomach, colon, rectum and liver cancers diagnosed in Changning District between 2010 and 2019 from the Shanghai Cancer Registry. We calculated age-standardized incidence and mortality rates, the risks of developing and dying from cancer, and the estimated annual percent changes. Between 2010 and 2019, 8619 new cases and 5775 deaths were registered with digestive tract cancers in the district. The age-standardized incidence rates (ASIRs) of liver cancer decreased steadily, whereas the ASIRs of stomach, colon and rectum cancers remained stable from 2010 to 2019. The age-standardized mortality rates (ASMRs) of stomach and liver cancers showed significant declining changes from 2010 to 2019 in both sexes, but that of colon and rectum cancers remained stable during the entire period. The risks of developing and dying from digestive tract cancers were substantially higher in men than women. The burden of digestive tract cancer and its disparities between sex and age group remain major public health challenges in urban Shanghai. To reduce the burden of digestive tract cancers, the government and researchers should develop and promote a healthy diet, organize a screening, and reduce the prevalence of smoking, alcohol drinking, and hepatitis B virus and hepatitis C virus infections.

show abstract

Potential Impact of Time Trend of Lifestyle Risk Factors on Burden of Major Gastrointestinal Cancers in China

Cited by 51 publications

References 66 publications

Tobacco Smoking and Gastrointestinal Cancer Risk

Tobacco Smoking and Gastrointestinal Cancer Risk

Typ-2-Diabetes mellitus und gastrointestinale Krebsvorsorge

Incidence, Mortality Features and Lifetime Risk Estimation of Digestive Tract Cancers in an Urban District of Shanghai, China

Contact Info

Product

Resources

About