Potential health risk in areas with high naturally-occurring cadmium background in southwestern China

Liu, Yizhang; Xiao, Tangfu; Baveye, Philippe C.; Zhu, Jianming; Ning, Zengping; Li, Huajun

doi:10.1016/j.ecoenv.2014.10.022

Cited by 89 publications

(39 citation statements)

References 59 publications

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“…Heavy metal contamination exists in wastewater of many industries such as metal plating, mining operations, surface finishing industry, tanneries, paper and pulp industries, fertilizer and pesticide industry, radiator manufacturing, energy and fuel production, aerospace and atomic energy installation, alloy industries and batteries industries. The presence of heavy metals, especially cadmium and cobalt ions, in the aquatic environment is of great concern as they are reported to be a source of major environmental and health hazards due to the unabated discharge of toxic effluents, their resistance to degradation, and adverse effects on both aquatic life and human consumption [1,2].…”

Section: Introductionmentioning

confidence: 99%

Activated carbon from Diplotaxis Harra biomass: Optimization of preparation conditions and heavy metal removal

Tounsadi

Khalidi

Abdennouri

et al. 2016

Journal of the Taiwan Institute of Chemical Engineers

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Section: Introductionmentioning

confidence: 99%

Activated carbon from Diplotaxis Harra biomass: Optimization of preparation conditions and heavy metal removal

Tounsadi

Khalidi

Abdennouri

et al. 2016

Journal of the Taiwan Institute of Chemical Engineers

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“…It is toxic for living organisms and carcinogenic for human beings (Liu et al, 2015;Seshadri et al, 2015). Although it is not an essential plant nutrient, Cd can be absorbed in larger quantities than other elements, such as cobalt and nickel, with no adverse effects on growth (Eshghi and Ranjbar, 2014;Seshadri et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

“…Cadmium also interacts with the metabolism of three essential metals: Ca, Zn, and Fe, generating their low intake by means of substitution and increase of competitive mobility with other elements (Goyer, 1997;Mora et al, 2016). The human body can absorb Cd through food, especially leaves and grains, water, or air: it accumulates and persists for a long time causing health problems (Liu et al, 2015). The World Health Organization (WHO) has considered a daily Cd intake of 0.83 μg kg -1 body weight or 58.1 μg Cd per person as toxic for human beings (WHO, 2010).…”

Section: Introductionmentioning

confidence: 99%

Absorption and distribution of cadmium of three maize hybrids in three environments

Retamal-Salgado¹,

Matus²,

Walter

et al. 2017

J. Soil Sci. Plant Nutr.

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Anthropogenic soil contamination with heavy metals has received much attention in recent years, especially cadmium (Cd), which is a very toxic element for human health and is exposure is mainly through contaminated food. Maize (Zea mays L.) is one of the most important cereals in the human diet that is characterized as species whose cultivars differ in Cd accumulation. Therefore, identifying and selecting low Cd-accumulating genetic material will contribute to reducing its ingestion. Among the agricultural crops that are important for Cd in the human diet is maize. Cadmium contents in three maize cultivars were grown under different environments conditions in Chile where soils were enriched with increasing Cd rates, were evaluated. Grain yield, Cd concentration in different plant tissues, and soil post-harvest, were evaluated. Results showed that grain yield was not affected by soil Cd; however, plant tissues generally exhibited differences in Cd concentration associated with the environment, La Serena showed the highest grain Cd accumulation (30 µg kg -1 ; P < 0.05). In addition, among cultivars, Pioneer showed the highest grain Cd concentration (19.5 µg kg -1 ; P < 0.05). Grain Cd concentration of the three maize cultivars were within the range cited in the bibliography as not toxic.

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“…In the past few decades, the toxicology of cadmium has become an important public and environmental health issue [23]. Cadmium is one of the heavy metal ions that can be hoarded in mammals and result in the chronic impairment of organs, especially the kidneys [4,24].…”

Section: Discussionmentioning

confidence: 99%

Phospholipase D1 Ameliorates Apoptosis in Chronic Renal Toxicity Caused by Low-Dose Cadmium Exposure

Deng

Wang

Geng

et al. 2020

BioMed Research International

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Exposure to cadmium (Cd), a common heavy metal used in industry, can result in long-term chronic toxicity. It has been well characterized that kidneys are the main organs that are targeted by toxicity, which can cause apoptosis, necrosis, and atrophy of renal tubular epithelial cells. However, the molecular mechanisms associated with Cd toxicity remain unclear. In this study, the expression of renal proteins in Sprague-Dawley rats exposed to chronic Cd was analyzed with iTRAQ proteomics. Bioinformatics analysis indicated that phospholipase D1 (PLD1) was significantly underexpressed and may correlate strongly with Cd-induced chronic kidney impairment. Previous studies have shown that PLD1 promotes cell proliferation and inhibits apoptosis, indicating that PLD1 may be implicated in the pathogenesis of kidney injury induced by Cd. Studies in vivo and in vitro all demonstrate that the mRNA and protein levels of PLD1 decrease significantly both in kidney tissue and in proximal tubular cell lines exposed to Cd. Overexpression of PLD1 and its downstream product PA could ameliorate Cd-induced apoptosis. Moreover, we identified that miR-122-5p was a regulatory miRNA of PLD1. miR-122-5p was overexpressed after Cd exposure and promoted cell apoptosis by downregulating PLD1 through binding the 3′UTR of the locus at 1761–1784 nt. In conclusion, our results indicated that PLD1 and its downstream PA were strongly implicated in Cd-induced chronic kidney impairment and could be a novel player in the defense against Cd-induced nephrotoxicity.

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Potential health risk in areas with high naturally-occurring cadmium background in southwestern China

Cited by 89 publications

References 59 publications

Activated carbon from Diplotaxis Harra biomass: Optimization of preparation conditions and heavy metal removal

Activated carbon from Diplotaxis Harra biomass: Optimization of preparation conditions and heavy metal removal

Absorption and distribution of cadmium of three maize hybrids in three environments

Phospholipase D1 Ameliorates Apoptosis in Chronic Renal Toxicity Caused by Low-Dose Cadmium Exposure

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