Potential Etiologies of Unexplained Infertility in Females

Galliano, Daniela; Pellicer, A.

doi:10.1007/978-1-4939-2140-9_13

Cited by 4 publications

(1 citation statement)

References 96 publications

(102 reference statements)

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“…When couples are not able to get pregnant with no identifiable reason, about 30% of infertility are defined as unexplained infertility and is a multifocal phenomenon of reproduction. Despite significant improvement made in diagnosis and care of reproduction, many couples still have no explanation for its infertility even after a series of most accurate diagnostical tests (Galliano & Pellicer, 2015). There is no uniform definition of unexplained infertility and it changes in literature and administration of therapy depends upon length of infertility period and age of the female spouse (Ray, Shah, Gudi & Homburg, 2012).…”

Section: Unexplained Infertilitymentioning

confidence: 99%

The effect of family structure and family support on women's coping with fertility treatments

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Introduction: The use of innovative fertility treatments contributed to the creation of new family structures that did not exist before, such as single-sex families and single-parent families. In the past, the only acceptable way to have a child was within marriage, nowadays fertility treatments solve various fertility problems and are technologically advanced and effective, yet many report repercussions for other areas of life, such as marital and social relations. Aim: To examine three main family structures: married couple, single mother and same-sex couple, as well as the coping of women undergoing fertility treatments, the difficulties they experience during treatment and their support systems. Materials and Methods: The study employed a mixed methodology, in which quantitative and qualitative data were gathered simultaneously to explore women's difficulties while undergoing fertility treatments and their support systems. a questionnaire created for the purpose that evaluates coping with the fertility treatments and their support systems if they exist. The questionnaire based on the literature review was distributed to 450 women who were undergoing fertility treatments in Israel. tracing and recruiting the participants was accomplished through sampling layers which were determined according to the research variable that corresponded with the population that was represented in the sample. All the data in the questionnaires were recorded in an Excel table according to the encoded questionnaire and analyzed with SPSS software. in addition, in phase ІІ based on the phenomenological design interviews to 15 patients overall. Data collection was quota samplethree clusters were selected and in each cluster a convenience sample was conducted until an affixed quota was filled. A qualitative content analysis approach (Graneheim & Lundman, 2004) was used to analyze the interview transcripts. Each interview was tape recorded, read multiple times to grasp the entirety of the data collected and transcribed verbatim. the written text was validated against the sound recordings. The transcribed text was divided into meaning unitsdepending on content, the meaning units were then divided into categories and subcategories by scrutinizing their similarities and differences, finally Then 5 central themes were created. Results: for the quantitative part 450 women participated in this study. Sample was divided into three groups-33.3% were married, 33.3% were single and 33.3% had a female partner with average age of 36.41. Results show that single women conducted more treatments (73.3%) in comparison with married women (65.3%) and women with female partner (54.7%). women with female partner reported higher partners' support in comparison with married women (F (1,298) =121.57, p <.01). Women who have no children are more negatively influenced in comparison with women with children, Finally, younger women have more support, but they also more negatively affected from fertility treatments in comparison with older women. in the qualitati...

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Section: Unexplained Infertilitymentioning

confidence: 99%

The effect of family structure and family support on women's coping with fertility treatments

Rimer¹

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How and Why to Define Unexplained Infertility?

et al. 2020

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Unexplained infertility represents up to 30% of all cases of infertility. It is a diagnosis of exclusion, where no cause for infertility may be identified in the investigation of the couple, be it anovulation, fallopian tube blockage, or severe male factor. Unexplained infertility therefore cannot be considered a diagnosis to which a specific treatment is directed, rather that it indicates a failure to reach a diagnosis of the true cause of infertility. In this review, we explore the evidence base and potential limitations of the current routine infertility assessment. We also aim to highlight the importance of considering the prognosis of each individual couple through the process of assessment and propose a reconsidered approach to treatment, targeted to the prognosis rather than the diagnosis. Ultimately, a better understanding of the mechanisms of infertility will reduce the number of couples diagnosed with “unexplained” infertility.

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Hysteroscopic evaluation of tubal peristaltic dysfunction in unexplained infertility

Yücel

Demirel

Kelekçi

et al. 2018

Journal of Obstetrics and Gynaecology

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It has been realised that rhythmic peristalsis of the ostia and tubes can be observed during hysteroscopy. The aim of this study was to examine the presence of tubal peristaltic dysfunction in unexplained infertility (UI). Hysteroscopy was performed in 35 women with UI and in 37 healthy fertile women. Bilateral tubal peristalses were assessed hysteroscopically by the observation of methylene blue injection and its transport to the Fallopian tubes. Tubal patency was evaluated with laparoscopic chromopertubation. Two women in control group (6.67%) and eight women in UI group (30.77%) had no tubal peristalsis, at least one tube with normal tubal patency. The difference was statistically significant (p = .019). Tubal peristaltic dysfunction may be a hidden cause of subfertility in women with bilateral patent Fallopian tubes. There is a definite need for larger trials to identify tubal peristaltic dysfunction as a cause of UI. Impact statement What is already known on this subject? Unexplained infertility has no identified pathophysiologic basis. It has been realised that rhythmic peristalsis of the ostia and tubes can be observed during hysteroscopy. What do the results of this study add? Tubal peristaltic dysfunction was detected in two tubes (3.70%) in a control group and nine tubes (19.57%) in women with unexplained infertility, when the tubes were patent. The difference was statistically significant (p = .012). What are the implications of these findings for clinical practice and/or further research? In cases of bilateral patent Fallopian tubes such as in unexplained infertility, tubal peristaltic dysfunction may be a hidden additional cause of subfertility.

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Potential Etiologies of Unexplained Infertility in Females

Cited by 4 publications

References 96 publications

The effect of family structure and family support on women's coping with fertility treatments

The effect of family structure and family support on women's coping with fertility treatments

How and Why to Define Unexplained Infertility?

Hysteroscopic evaluation of tubal peristaltic dysfunction in unexplained infertility

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