Potential Effects of Food Processing Byproducts on Neurological and Immunological Disorders of Obese Rats

Abstract

The present study aims to explore the effect of three byproducts that result from food processing processes, namely onion and bananas peels, and apricot seeds on neurological and immunological disorders of obese rats. Feeding of rats on diet induced obesity (DIO) leads to increase the BW than the control group. At the end of the experiment (8 weeks), rats of the normal group recorded 131.33% of baseline for the BW while obese group was 197.25% of baseline. Replacement of diets starch with banana peel powder (BPP), onion skin powder (OSP), apricot seeds powder (ASP) and their mixture induced significant decreasing on BW of the obese rats which recorded 177.85, 155.41, 173.59 and 144.83% of baseline, respectively. The higher effect on weigh decreasing was recorded for the plant parts mixtures followed by OSP, ASP and BPP, respectively. On the other side data has demonstrated the potency of the selected food processing byproducts including BPP, ROSP, ASP and their mixture to ameliorate the neurological (dopamine and serotonin content and acetylcholine esterase activity) and immunological (serum albumin and tumor necrosis factorα content, and protease activity) disorders in obese rats. These findings provide a basis for the use of the selected food processing byproducts for the prevention and early treatment of obesity. Also, the data support the benefits of dietary modification, including food processing byproducts supplementation, in alleviating neurological and immunological disorders associated obesity.

Productivity Performance of Musa AAA Under Diferents Planting Densities and Two Cultivars (Grand Nain and Williams) in Banana Intensive Agrosystems in the Agneby-Tiassa Region, Côte D'ivoire

“…They can protect human body against damage by free radicals, which attack macromolecules including membrane lipids, proteins and DNA, lead to many health disorders/diseases including cancers, diabetes, heart vascular diseases, aging, inflammatory diseases, obesity, anemia, etc. [25,30,[107][108][109][110][111].…”

“…Generally, several previous studies indicated that that the level of MDA in the serum is a good marker of lipid peroxidation /oxidative stress, which is closely related to the pathogenesis of many diseases, including obesity [26,109,110,128,129,139]. It is one of the most important compounds in lipid peroxidation products and major product of the oxidation of polyunsaturated fatty acids, lipid hydroperoxides and conjugated dienes which found to be increased in plasma from obese subjects in many clinical studies [129,144].…”

Full Profiling of The Orange By-Products and Their Potential Effects with Chromium on Obesity Complications in Rats

“…A metabolic disease known as obesity is brought on by an excess of calories consumed and a lack of physical exercise [1]. Obesity is associated with several chronic circumstances, containing hypertension, dyslipidemia, and coronary heart ailments [2,3]. Body mass index (BMI), which is expressed as the weight in Kgs divided by the square of the height in meters (kg/m2), is a standard tool for determining the prevalence of bulky and obesity.…”