Potential effects of alginate–pectin biocomposite on the release of folic acid and their physicochemical characteristics

Pour, Pegah Kiaei; Alemzadeh, Iran; Vaziri, Asma Sadat; Beiroti, Ahmad

doi:10.1007/s13197-020-04369-7

Cited by 18 publications

(7 citation statements)

References 27 publications

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“…This was also consistent with our textural analysis results showing that higher amounts of pectin produced a weaker gel structure that could not retain the EA in the structure. The pectin can reduce the regularity of the structure, leading to a weak network formation and thus forming more unstable matrices 33 . Similar to our results, it was reported that EE% of mint oil was reduced by partially replacing pectin with alginate, 11 whereas in another study the EE% of folic acid into alginate–pectin gels was increased by pectin addition 34 .…”

Section: Resultssupporting

confidence: 90%

Electrosprayed chitosan‐coated alginate–pectin beads as potential system for colon‐targeted delivery of ellagic acid

et al. 2021

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BACKGROUND: Ellagic acid (EA), a potent dietary antioxidant, has limited bioavailability owing to its rapid absorption in the stomach and small intestine, and EA is transformed to more bioavailable compoundsurolithinsin the colon. An encapsulation system that sustains the release of EA in the gastrointestinal system and delivers more EA into the colon could improve the oral bioavailability of EA. Electrosprayed EA-loaded alginate-pectin beads were produced and coated with low-(LC) and highmolecular-weight chitosan (HC). The EA release from uncoated and coated beads under simulated gastrointestinal conditions was evaluated. The samples were characterized by particle size, gel strength, scanning electron microscopy (SEM) and Fourier transform infrared (FTIR) analysis.RESULTS: The encapsulation efficiency (EE%) of EA ranged from 49.53% to 69.85% for uncoated beads, which was elevated up to 86.50% by coating, and LC coating provided higher EE%. Pectin addition to alginate and chitosan coating reduced the gel strength and changed the size depending on the molecular weight of chitosan. SEM images of pectin-added beads showed fewer cracks but more wrinkles, and chitosan coating presented more aggregated surfaces. The ionic interaction of alginatepectin-chitosan and the entrapment of EA were confirmed by FTIR. In the gastric medium, EA release was very low from uncoated beads (15.2-19.8%), and totally restricted by chitosan coating. In the intestinal stage, EA release from LC-coated alginate-pectin beads was only 18%, and it was between 55% and 65% for uncoated or HC-coated counterparts.CONCLUSION: The LC-coated alginate-pectin beads could be further explored as a potential system for colon-targeted delivery of EA.

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Section: Resultssupporting

confidence: 90%

Electrosprayed chitosan‐coated alginate–pectin beads as potential system for colon‐targeted delivery of ellagic acid

et al. 2021

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“…Pectin is well suited both as a coating and a gelling material. The alginate–pectin mixture has been shown to provide a protective effect by forming a strong gel matrix under acidic conditions [ 40 ]. Therefore, this mixture has been successfully used for the encapsulation of several nutrients and drugs, such as vitamins [ 13 ], essential oils [ 41 ], and proteins [ 42 ].…”

Section: Resultsmentioning

confidence: 99%

Microencapsulation of Tangeretin in a Citrus Pectin Mixture Matrix

Cameron

Manthey

Hunter

et al. 2020

Foods

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The objectives of this research were to microencapsulate tangeretin, and to evaluate the basic characteristics of the microcapsule products. Tangeretin is a polymethoxyflavone (PMF) which has been revealed to possess various health benefits and is abundant in tangerine and other citrus peels. Microencapsulation technology is widely employed in the food and pharmaceutical industries to exploit functional ingredients, cells, and enzymes. Spray drying is a frequently applied microencapsulation method because of its low cost and technical requirements. In this research, tangeretin dissolved at different concentrations in bergamot oil was microencapsulated in a citrus pectin/sodium alginate matrix. The resulting microcapsule powder showed promising physical and structural properties. The retention efficiency of tangeretin was greater at a concentration of 2.0% (98.92%) than at 0.2% (71.05%), probably due to the higher temperature of the emulsion during the homogenizing and spray-drying processes. Encapsulation efficiency was reduced with increased concentration of tangeretin. Our results indicate that tangeretin could be successfully encapsulated within a citrus pectin/sodium alginate matrix using bergamot oil as a carrier.

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“…Extrusion is the encapsulating method for kenaf seed oil in pectin microspheres [75], as well as in pectin/alginate structuring for the controlled release of polyphenols from papaya [76] and folic acid [82] to protect Lactobacillus acidophilius in gastrointestinal fluids [78] and make pectin-coated nanoliposomes [83], among others.…”

Section: Extrusionmentioning

confidence: 99%

Pectin Microspheres: Synthesis Methods, Properties, and Their Multidisciplinary Applications

2022

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There is great contemporary interest in using cleaner technologies through green chemistry and utilizing biopolymers as raw material. Pectin is found on plant cell walls, and it is commonly extracted from fruit shells, mostly apples or citrus fruits. Pectin has applications in many areas of commercial relevance; for this reason, it is possible to find available information about novel methods to transform pectin and pursuing enhanced features, with the structuring of biopolymer microspheres being highly cited to enhance its activity. The structuring of polymers is a technique that has been growing in recent decades, due to its potential for diverse applications in various fields of science and technology. Several techniques are used for the synthesis of microspheres, such as ionotropic gelation, extrusion, aerosol drying, or emulsions, with the latter being the most commonly used method based on its reproducibility and simplicity. The most cited applications are in drug delivery, especially for the treatment of colon diseases and digestive-tract-related issues. In the industrial field, it is used for protecting encapsulated compounds; moreover, the environmental applications mainly include the bioremediation of toxic substances. However, there are still many possibilities for expanding the use of this biopolymer in the environmental field.

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Potential effects of alginate–pectin biocomposite on the release of folic acid and their physicochemical characteristics

Cited by 18 publications

References 27 publications

Electrosprayed chitosan‐coated alginate–pectin beads as potential system for colon‐targeted delivery of ellagic acid

Electrosprayed chitosan‐coated alginate–pectin beads as potential system for colon‐targeted delivery of ellagic acid

Microencapsulation of Tangeretin in a Citrus Pectin Mixture Matrix

Pectin Microspheres: Synthesis Methods, Properties, and Their Multidisciplinary Applications

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