Potential Effects of A Flavonoid, Hesperidin on SARS-CoV-2 Disease

Khazdair, Mohammad Reza

doi:10.5603/arm.a2021.0093

Advances in Respiratory Medicine

2021

DOI: 10.5603/arm.a2021.0093

|View full text |Cite

Potential Effects of A Flavonoid, Hesperidin on SARS-CoV-2 Disease

Mohammad Reza Khazdair

Abstract: This article is available in open access under Creative Common Attribution-Non-Commercial-No Derivatives 4.0 International (CC BY-NC-ND 4.0) license, allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

Publication Types

Select...

Article1

Relationship

Self Cite1

Independent0

Authors

Journals

Cited by 1 publication

(1 citation statement)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover, alkaloids and flavonoids showed antimicrobial and larvicidal effects (Naghibi et al, 2005). The possible advantageous effects of Nigella sativa and its ingredients, thymoquinone, as well as natural products and flavonoids on SARS-CoV-2, were also reported (Khazdair, 2021;Khazdair, Anaeigoudari, et al, 2021).…”

mentioning

confidence: 97%

Effects of Lamiaceae family plants and their bioactive ingredients on coronavirus‐induced lung inflammation

Kianmehr,

Khazdair,

Abbasnezhad

et al. 2023

Food Science & Nutrition

Self Cite

View full text Add to dashboard Cite

Coronaviruses (CoVs) are a family of viruses that cause infection in respiratory and intestinal systems. Different types of CoVs, those responsible for the SARS‐CoV and the new global pandemic of coronavirus disease 2019 in people, have been found. Some plants were used as food additives: spices and dietary and/or medicinal purposes in folk medicine. We aimed to provide evidence about possible effects of two Lamiaceae family plants on control or treatment of CoVs‐induced inflammation. The keywords including coronaviruses, Thymus vulgaris, Zataria multiflora, thymol, carvacrol, antivirus, and anti‐inflammatory and antioxidant effects were searched in various databases such as PubMed, Web of Sciences (ISI), and Google Scholar until September 2022. The medicinal herbs and their main ingredients, thymol and carvacrol, showed antiviral properties and reduced inflammatory mediators, including IL‐1β; IL‐6, and TNF‐α, at both gene and protein levels but increased the levels of IFN‐γ in the serum as anti‐inflammatory cytokine. These medicinal herbs and their constituents also reduce oxidative stress and enhance antioxidant capacity. The results of molecular docking analyses also indicated that polyphenol components such as thymol, carvone, and carvacrol could inhibit the entry of the viruses into the host cells in molecular docking analyses. The antiviral, anti‐inflammatory, and antioxidant effects of these plants may be due to actions of their phenolic compounds that modulate immune response and may be useful in the control and treatment of CoV‐induced lung disorder.

show abstract

mentioning

confidence: 97%

Effects of Lamiaceae family plants and their bioactive ingredients on coronavirus‐induced lung inflammation

Kianmehr,

Khazdair,

Abbasnezhad

et al. 2023

Food Science & Nutrition

Self Cite

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Potential Effects of A Flavonoid, Hesperidin on SARS-CoV-2 Disease

Cited by 1 publication

References 24 publications

Effects of Lamiaceae family plants and their bioactive ingredients on coronavirus‐induced lung inflammation

Effects of Lamiaceae family plants and their bioactive ingredients on coronavirus‐induced lung inflammation

Contact Info

Product

Resources

About