Potential drug interactions: recognising and minimising the risks

Reddy, Bhavana

doi:10.12968/npre.2006.4.10.22320

Cited by 5 publications

(5 citation statements)

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“…An interaction can also be said to occur if the effects of a drug are altered by the presence of food, drink or herbal medicines (Reddy 2006a). Adverse drug interactions occur when two or more drugs interact in such a way that the effectiveness or toxicity of one or more of the drugs is altered.…”

Section: Time Outmentioning

confidence: 99%

“…For example, patients taking the anticoagulant warfarin who are given the anti-tuberculous drug rifampicin will require extra warfarin to maintain an adequate anticoagulant effect (Reddy 2006a). For example, patients taking the anticoagulant warfarin who are given the anti-tuberculous drug rifampicin will require extra warfarin to maintain an adequate anticoagulant effect (Reddy 2006a).…”

Section: Time Outmentioning

confidence: 99%

“…It is impossible to remember every potential drug interaction, but it is useful for prescribers to know where they can access information about adverse drug interactions (Reddy 2006a). If the result of the interaction is to increase or reduce the effect of a drug then the dose can be adjusted to prevent adverse effects.…”

Section: Time Outmentioning

confidence: 99%

“…If the result of the interaction is to increase or reduce the effect of a drug then the dose can be adjusted to prevent adverse effects. However, it is important not to be too reliant on these systems as they may not detect every possible interaction (Reddy 2006a). It is impossible to remember every potential drug interaction, but it is useful for prescribers to know where they can access information about adverse drug interactions (Reddy 2006a).…”

Section: Time Outmentioning

confidence: 99%

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Non-medical prescribing using the British National Formulary

Kaufman

2008

Nursing Standard

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This article explores how to maximise efficient use of the British National Formulary (BNF) within the context of non-medical prescribing. It provides an overview of the layout of the BNF and identifies how the publication can be used to detect contraindications and potential drug interactions. The detection, recording and reporting of adverse drug reactions are also explored. In addition, prescription writing standards and the meaning of unlicensed and off laobe medicines are discussed.

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Section: Time Outmentioning

confidence: 99%

Section: Time Outmentioning

confidence: 99%

Section: Time Outmentioning

confidence: 99%

Section: Time Outmentioning

confidence: 99%

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Non-medical prescribing using the British National Formulary

Kaufman

2008

Nursing Standard

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“…Patients in the ICU are administered more drugs than inpatients in other clinics, and this increases the risk of developing drug-drug interactions (Gülhan, 2013;Lima & Cassiani, 2009;Hammes et al, 2008). Drug-drug interactions (DDI) occur when more than one drug is administered together and can change the efficacy or toxicity of one or more drugs (Reddy, 2006). With the occurrence of DDI, it causes the absorption, distribution, metabolism or mechanism of action of the administered drug to be impaired on another drug (European Medicines Agency, 2010).…”

Section: Introductionmentioning

confidence: 99%

Knowledge and Practices of Nurses Working in Intensive Care on Drug-Drug Interaction

CAN

Yayan

2022

JSRMBS

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Purpose:This study was conducted to examine the knowledge and practices of nurses working in the intensive care unit about drug-drug interaction. Materials and Methods: This study was conducted with 186 intensive care nurses working in shifts in 12 intensive care units. "Nurse information form", "Drug-drug interaction questionnaire" prepared by the researcher, and "nurse observation form" were used in data collection. The data obtained from the study were evaluated in computer environment using frequency, percentage distribution and Chi-square test. Results:In the study, 76.3% of the nurses working in the intensive care unit reported that they did not know which of the drug pairs they encountered frequently caused drug-drug interactions. When the drugs administered by the nurses were examined, it was determined that 34.4% of them had the potential for drug-drug interaction. It was found that nurses' potential drug-drug interaction practices, staff status and working styles, and working time in the institution, profession and intensive care unit were not effective. It was determined that there were significant differences between the intensive care units (p=0.043) in the drug-drug interaction practices encountered. Conclusion:It was determined that the nurses did not have the desired level of knowledge about drug-drug interactions and interacting drug pairs, and there were differences between the intensive care units where they worked. It is recommended to increase the level of knowledge by giving regular trainings to nurses on drug-drug interaction.

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Identifying polypharmacy in the primary care setting

Kaufman

2016

Practice Nursing

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Polypharmacy—the use of multiple medicines—is commonly seen in primary care, particularly in older patients, and can be defined as appropriate or problematic. Polypharmacy can be associated with complex networks of interactions ( Duerden et al, 2013 ) and the risk of drug interactions increases significantly the more medicines the patient takes ( Karalliedde et al, 2010 ). The incidence of adverse drug reactions has been shown to increase with the number of medicines taken and age also plays a factor. Nurses working in general practice who care for patients with multi-morbidities and polypharmacy are ideally placed to identify issues related to the use of multiple medicines and reduce the risks of adverse events.

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Potential drug interactions: recognising and minimising the risks

Cited by 5 publications

References 1 publication

Non-medical prescribing using the British National Formulary

Non-medical prescribing using the British National Formulary

Knowledge and Practices of Nurses Working in Intensive Care on Drug-Drug Interaction

Identifying polypharmacy in the primary care setting

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