Over the last decade, carbon emissions due to forest degradation in the Brazilian Amazon, linked primarily to logging and wildfires, have become larger than carbon emissions due to deforestation. Climatic and ecological processes affect the landscape’s flammability, while socio-economic processes influence fire use for land management. To limit fire occurrence and its impacts, and lower the risk of rainforest die-off, it is important to understand the drivers of managed and accidental fires. We used deforestation and land use maps, to classify satellite-detected fires in the Brazilian Amazon into deforestation fires, forest fires and agricultural fires. We fitted Bayesian spatiotemporal models for the 2011-2015 and 2016-2020 periods to estimate the association between the three types of fires and potential drivers. We found forest fires are associated with forest cover fragmentation and the distance from forest-agricultural edges. Deforestation fires are closely linked to pastures and became increasingly frequent in the isolated parts of the Brazilian Amazon, while agricultural fires are also frequent in croplands. Protected areas and indigenous lands were associated with fewer deforestation fires and forest fires than unprotected areas. However, sustainable use areas and indigenous land were associated to more deforestation fires over the last period. Reducing wildfire occurrence in the region will require the adoption of agricultural systems that are less reliant on the use of fire, together with reinforced environmental policies to reduce deforestation in the face of weakening forest resource governance.