Potential Causative Factors for Saccular Disorders: Association with Smoking and Other Laryngeal Pathologies

Cohen, Oded; Tzelnick, Sharon; Shapira‐Galitz, Yael; Shoffel‐Havakuk, Hagit; Hain, Moshe; Halperin, Doron; Lahav, Yonatan

doi:10.1016/j.jvoice.2017.01.004

Cited by 6 publications

(5 citation statements)

References 31 publications

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“…All parameters showed a general improvement after the endoscopic resection although none of these differences were statistically significant, due to the small number of patients. Also, a systematic review of the reports made on saccular cysts in the current literature was conducted by PubMed search on the basis of keywords and their synonyms relating to saccular cysts with exclusion of case reports (Table 3) [2,7-9]. The search was carried out covering the period up to 2017.…”

Section: Resultsmentioning

confidence: 99%

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Clinical Characteristics and Management of Saccular Cysts: A Single Institute Experience

Kim

Ahn

et al. 2019

Clin Exp Otorhinolaryngol

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Objectives A saccular cyst is defined as a dilated saccule of the larynx, filled with mucus, and is located between the false vocal cords and the thyroid cartilage. Although this uncommon laryngeal condition is benign in nature, it could lead to dyspnea, stridor, and airway obstruction, depending on its size and location. Furthermore, some saccular cysts have been associated with laryngeal carcinoma. This study aimed to characterize this rather uncommon laryngeal condition to aid in determining the proper management of this pathology. Methods Medical records were retrospectively reviewed of all patients with saccular cysts diagnosed and treated between 2006 and 2017 at a tertiary otolaryngologic care center. Results Seven patients with saccular cysts were identified (male:female=2:5; mean age, 34.1 years); two were pediatric patients. Surgical intervention was performed in all patients by laryngo-microsurgery using CO 2 laser. There was no recurrence after the initial surgical treatment. Conclusion Saccular cysts can be managed endoscopically using CO 2 laser, without requiring an external approach. Therefore, an endoscopic approach should be actively considered for an optimal treatment outcome.

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Section: Resultsmentioning

confidence: 99%

“…However, surgical excision via an external approach is required for the treatment of huge lateral saccular cysts. With advancements in laryngeal endoscopic technique, most studies performed since 2010 have indicated that endoscopic excision with CO 2 laser is a successful and reliable method for anterior and combined saccular cysts [2,8,9].…”

Section: Discussionmentioning

confidence: 99%

Clinical Characteristics and Management of Saccular Cysts: A Single Institute Experience

Kim

Ahn

et al. 2019

Clin Exp Otorhinolaryngol

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“…The condition is characterized by deposition of mucoid gelatinous soft tissue within the superficial lamina propria (SLP) immediately beneath the surface epithelium (Reinke's space) 4 . Although its etiology is still unclear, the condition seems to be related to prolonged laryngeal irritation usually associated with smoking, voice abuse, and acid reflux 5–12 …”

Section: Introductionmentioning

confidence: 99%

“…4 Although its etiology is still unclear, the condition seems to be related to prolonged laryngeal irritation usually associated with smoking, voice abuse, and acid reflux. [5][6][7][8][9][10][11][12] Polypoid changes in RE patients can range from mild fullness and minor symptoms to severe exophytic edema with significant voice and airway symptoms. 13 This varied presentation created the need for classification systems based on the severity of polypoid changes noted on endoscopy.…”

Section: Introductionmentioning

confidence: 99%

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Voice outcomes in high‐grade Reinke's edema: Comparing microflap excision and microdebrider surgery

Bentsianov,

Liang,

Bentsianov

2023

Laryngoscope Investig Oto

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ObjectivesPatients presenting with hoarseness and diagnosed with high‐grade Reinke's edema (RE) will often require surgical intervention for polypoid changes of the true vocal folds. We compared patient outcomes in patients who had microflap or microdebrider excision surgeries.MethodsPatients with the diagnosis of grade II or grade III RE based on laryngoscopy or videostroboscopy who failed conservative management underwent surgery using the standard excision practice of the primary surgeon. Voice outcomes were compared using VHI‐30 (Voice Handicap Index), V‐RQOL (Voice‐Related Quality of Life), and MPT (maximum phonation time) preoperatively and at 1‐month and 6‐months postoperatively.ResultsOf the 115 patients included, there were 46 RE grade II patients and 69 RE grade III patients with 52 patient undergoing microflap surgery and 63 patients undergoing microdebrider surgery. Both procedures resulted in significant improvement in VHI‐30, V‐RQOL, and MPT at 1‐month and 6‐months postoperatively. The microdebrider group had better 6‐month VHI scores (40.84) than the microflap group (44.54) (CI −7.27 to −0.12). The microdebrider group also had better 6‐month V‐RQOL measures (62.56) than the microflap group (57.79) (CI 0.38–9.16).ConclusionBoth microflap excision and microdebrider excision for high‐grade RE lesions resulted in significant improvement in VHI‐30, V‐RQOL, and MPT at 1‐month and 6‐months postoperatively with the microdebrider excision group scoring statistically significantly better at 6 months in comparison to the microflap group. Overall, the results support the use of both surgical modalities for treating high‐grade RE patients.Level of evidence3.

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Endoscopic Excision of Saccular Cyst

Simpson,

Rosen

2024

Operative Techniques in Laryngology

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Potential Causative Factors for Saccular Disorders: Association with Smoking and Other Laryngeal Pathologies

Cited by 6 publications

References 31 publications

Clinical Characteristics and Management of Saccular Cysts: A Single Institute Experience

Clinical Characteristics and Management of Saccular Cysts: A Single Institute Experience

Voice outcomes in high‐grade Reinke's edema: Comparing microflap excision and microdebrider surgery

Endoscopic Excision of Saccular Cyst

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