Potential Benefits of Antioxidant Phytochemicals on Endogenous Antioxidants Defences in Chronic Diseases

Pasini, Anna Maria Fratta; Cominacini, Luciano

doi:10.3390/antiox12040890

Cited by 7 publications

(3 citation statements)

References 35 publications

(39 reference statements)

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“…Unique polyphenol subgroups found in whole grain rice of various colors have a favorable effect on human health [1]. Increased whole grain consumption is strongly linked to a lower prevalence of chronic illnesses, according to the numerous epidemiological research [24]. Recent studies have shown that colored rice has high levels of antioxidants [2], which were identified by various cutting-edge method as ultra-performance liquid chromatography (UPLC), high-performance liquid chromatography (HPLC), liquid chromatography-mass spectrometry, ultra-HPLC Online-ABTS system.…”

Section: Bioactive Compounds In Pigmented Rice Cultivarsmentioning

confidence: 99%

Recent important insight into nutraceuticals potential of pigmented rice cultivars: A promising ingredient for future food

Loan,

Vinh,

Tai

2024

J App Biol Biotech

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Many phytochemicals and nutraceuticals have historically been known to have positive effects on health, especially in ancient and modern health systems. Due to the presence of color, rice, a common basic meal, has anti-inflammatory, anti-cancer, and nutritional effects. It has been shown that polyphenols in rice extracts can alter important signaling pathways involved in cancer. It is also commonly used for its nutritional benefits and to promote general health. We cover the phytochemicals and potential health benefits of colored rice in this brief review. This article discusses the relatively limited in vivo research that has been done to date to formally establish the nutritional potential of rice. Importantly, the available literature supports and promotes the use of colored rice as an anti-diabetic agent, source of prebiotics, and cancer-preventing agent. To methodically evaluate the clinical efficacy and potential of colored rice, future research must focus on properly planned clinical trials in cancer and diabetes patients. Further scientific research on rice extract alone or colored rice flour as a nutritional food and/or functional food could pave the way for new ways to explore the health benefits of rice from experiment to the clinic to prevent disease. ARTICLE HIGHLIGHTS• This paper presents an analysis of colored rice, focusing on its bioactive chemical content, concentration, activities, and potential health benefits • The updated information on the bioactive compounds of colored/ pigmented rice varieties was presented • The link between the antioxidants and health benefits was providing by current researches • The current status of the application of pigmented rice was summarized, and further application was suggested • Pigmented rice could have more potential in future food with high promising nutraceutical properties.

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Section: Bioactive Compounds In Pigmented Rice Cultivarsmentioning

confidence: 99%

Recent important insight into nutraceuticals potential of pigmented rice cultivars: A promising ingredient for future food

Loan,

Vinh,

Tai

2024

J App Biol Biotech

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“…In general, the existence of hydroxyl groups is mainly responsible for the antioxidant capacity of phenolic compounds, which possess the ability to donate electrons [13]. These phenolic compounds also boost the antioxidant activities of cells by stimulating the synthesis of endogenous antioxidant molecules like glutathione peroxidase, superoxide dismutase, and catalase within the cell and inducing their defense mechanisms through the regulation of multiple signaling pathways [14][15][16].…”

Section: Introductionmentioning

confidence: 99%

“…Several existing studies have revealed that phenolic substances can suppress the generation of free radicals, break down peroxides and inactive metal ions, and hinder the process of oxygen scavenging within biological systems that ultimately defend against many oxidative diseases [17]. Thus, phenolic compounds from medicinal plants have recently gained extensive attention because of their plentiful pharmacological actions such as preventing neurodegenerative diseases, body inflammation, cancers, diabetes, osteoporosis, and cardiovascular problems [14]. Given the intrinsic utility and broad spectrum of potential uses in the pharmaceutical sector, it is crucial to concentrate on phenolic extraction.…”

Section: Introductionmentioning

confidence: 99%

Optimization and Characterization of Phenolic Extraction Conditions and Antioxidant Activity Evaluation of Adenanthera pavonina L. Bark

Begum,

Hossain,

Adnan

et al. 2023

Plants

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The presence of high levels of secondary metabolites in medicinal plants can significantly influence the progress of drug development. Here, we aimed to maximize phenolic extraction from Adenanthera pavonina L. stem bark using various solvents such as ethyl acetate, methanol, petroleum ether, and chloroform. A response surface method (RSM) with a central composite design (CCD) statistical technique was applied to optimize the extraction process, employing three important extracting parameters such as extraction time (h), temperature (°C), and solvent composition (% v/v of methanol/water) to obtain the highest phenolic content. Total phenolic content (TPC) and antioxidant activity (IC50 of extract’s DPPH radical scavenging activity) were used as response variables to find the influence of these extracting parameters. Among the various solvents used, methanol extract showed the highest contents of phenolics and the maximum level of antioxidant activity with a lower IC50 value. The notable TPC and IC50 value of the extract’s DPPH radical scavenging capacity were found to be 181.69 ± 0.20 mg GAE/g dry tissue and 60.13 ± 0.11 mg/mL, respectively, under the optimal conditions with a solvent composition of 71.61% (v/v) of methanol/water, extraction temperature of 42.52 °C, and extraction time of 24 h. The optimized extract of A. pavonina stem bark was further subjected to HPLC analysis, where six phenolic compounds, including coumarin, p-coumaric acid, chlorogenic acid, sinapic acid, gallic acid, and caffeic acid, were identified along with their respective quantities. Overall, the findings of this study uncover a low-cost analytical model for maximizing phenolic extraction from A. pavonina bark with enhanced antioxidant activity.

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Evaluation of functional extrudates enriched with essential oils for enhanced stability

Laina,

Drosou,

Krokida

2024

Food and Bioproducts Processing

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Potential Benefits of Antioxidant Phytochemicals on Endogenous Antioxidants Defences in Chronic Diseases

Abstract: Chronic diseases and cancer are worldwide health problems which result in death and disability for millions of people [...]

Cited by 7 publications

References 35 publications

Recent important insight into nutraceuticals potential of pigmented rice cultivars: A promising ingredient for future food

Recent important insight into nutraceuticals potential of pigmented rice cultivars: A promising ingredient for future food

Optimization and Characterization of Phenolic Extraction Conditions and Antioxidant Activity Evaluation of Adenanthera pavonina L. Bark

Evaluation of functional extrudates enriched with essential oils for enhanced stability

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