Potential application of anti-osteoporotic therapy to relieve sarcopenia in the elderly

Abstract

Sarcopenia is a progressive and systemic skeletal muscle disorder associated with aging that- usually occurs with age in the elderly.Sarcopenia currently lacks effective pharmacological treatment modalities. Multiple pharmacological intervention modalities are available for osteoporosis, a comprehensive disease characterized by decreased systemic bone mass, degradation of bone microarchitecture, and increased bone fragility. Several recent studies have shown an extremely strong correlation between sarcopenia and osteoporosis, leading to the concept of “osteosarcopenia”. Therefore, it is possible to alleviate sarcopenia simultaneously by improving osteoporosis.