Potential Antiradiation Compounds II. Extension of the Nitro-Thiolacetate Route

Bhat, K. V.; McCarthy, Walter C.

doi:10.1002/jps.2600531231

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* Pitressin Parke-davis Detroit Mich1

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1966

1969

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“…Procaine (191) and several of its derivatives, particularly p-nitro procainamides (192), have good protective activity. In this connection, l-phenyl-lacetthio-2-nitroethane and its higher homolog were active in mice, while the corresponding amino compound, 1 -phenyl-2-aminoethanethiol, was inactive (193). 4-H ydroxybutyric acid and 6-phosphonogluconolactone, substances which stimulate turnover of NADP.…”

Section: * Pitressin Parke-davis Detroit Michmentioning

confidence: 92%