Abstract:Osteoporosis is a systemic skeletal disease characterized by low bone mass, that can result in fracture when injury, for example, due to a traffic accident. This study aimed to identify secondary metabolites from Zingiber officinale that potentially inhibit cathepsin K, a critical enzyme that caused osteoporosis. In this study, a molecular docking of 102 bioactive compounds from Zingiber officinale against cathepsin K (PDB ID: 4X6I) was conducted. Ligand preparation was performed using JChem and Schrödinger’s … Show more
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