2017
DOI: 10.1590/0104-6632.20170342s20150522
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Abstract: -The optimization of culture medium with statistical methods is widely used in filamentous fungi glycosyl hydrolase production. The implementation of such methodology in bioreactors is very expensive as it requires several pH-controlled systems operating in parallel in order to test a large number of culture media components. The objective of this study was to evaluate potassium biphthalate buffer for pH control, which allows the optimization studies to be performed in shake flasks.The results have shown that … Show more

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Cited by 4 publications
(1 citation statement)
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“…It has also got excellent soft- and hard-tissue integrity. [ 13 17 18 21 ] Potassium hydrogen phthalate – an acidic salt compound that acts as a buffer and stabilizes the pH of the reagents,[ 22 ] and dimethyl sulfoxide – an inert solvent which acts as a penetration enhancer. It is also shown to improve the immediate and long-term bond strength of dentin.…”
Section: Discussionmentioning
confidence: 99%
“…It has also got excellent soft- and hard-tissue integrity. [ 13 17 18 21 ] Potassium hydrogen phthalate – an acidic salt compound that acts as a buffer and stabilizes the pH of the reagents,[ 22 ] and dimethyl sulfoxide – an inert solvent which acts as a penetration enhancer. It is also shown to improve the immediate and long-term bond strength of dentin.…”
Section: Discussionmentioning
confidence: 99%