Postural instability, frontotemporal dementia, and ophthalmoplegia: Clinicopathological case

Cardoso, Francisco; Hodges, John R.; Evans, Andrew; Révész, Tamás; Williams, David R.

doi:10.1002/mds.23359

Cited by 2 publications

(1 citation statement)

References 22 publications

(28 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[2] Patients with attention and cognitive disorders are at risk of disequilibrium in this automatic, unconscious act of walking due to inability to concentrate in dual tasking. [3][4][5][6][7][8][9][10][11][12][13][14] There is evidence for abnormal equilibrium in Ad and motor dysfunction in FTD. [15][16][17] This can increase morbidity significantly in these patients.…”

Section: Introductionmentioning

confidence: 99%

Quantitative Balance and Gait Measurement in Patients with Frontotemporal Dementia and Alzheimer Diseases: A Pilot Study

Velayutham

Chandra

Bharath

et al. 2017

Indian Journal of Psychological Medicine

View full text Add to dashboard Cite

Introduction:Alzhiemers disease and Frontotemporal dementia are common neurodegenerative dementias with a wide prevalence. Falls are a common cause of morbidity in these patients. Identifying subclinical involvement of these parameters might serve as a tool in differential analysis of these distinct parameters involved in these conditions and also help in planning preventive strategies to prevent falls.Patients and Methods:Eight patients in age and gender matched patients in each group were compared with normal controls. Standardizes methods of gait and balance aseesment were done in all persons.Results:Results revealed subclinical involvement of gait and balancesin all groups specially during divided attention. The parameters were significantly more affected in patients. Patients with AD and FTD had involement of over all ambulation index balance more affected in AD patients FTD patients showed step cycle, stride length abnormalities.Discussion:There is balance and gait involvement in normal ageing as well as patients with AD and FTD. The pattern of involvement in AD correlates with WHERE pathway involvement and FTD with frontal subcortical circuits involvement.Conclusion:Identification the differential patterns of involvement in subclinical stage might help to differentiate normal ageing and the different types of cortical dementias. This could serve as an additional biomarker and also assist in initiating appropriate training methods to prevent future falls.

show abstract