Posttraumatic Stress Disorder Symptoms After Bone Marrow Transplantation for Breast Cancer

Jacobsen, Paul B.; Widows, Michelle R.; Hann, Danette; Andrykowski, Michael A.; Kronish, Lori E.; Fields, Karen K.

doi:10.1097/00006842-199805000-00026

Cited by 142 publications

(98 citation statements)

References 16 publications

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“…Reactions can include a wide range of depressive and anxious symptoms, intrusive thoughts and thoughts of avoidance [6]. The way in which an individual adjusts to a cancer diagnosis may be mediated by a host of pre-existing psychosocial factors that can influence the cancer experience.…”

Section: Distress and Emotional Healthmentioning

confidence: 99%

Physical Activities and Distress among Participants of a Cancer Wellness Centre: A Community-Based Pilot Study

Leimanis

Fitzpatrick²

2014

Int J Phys Med Rehabil

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Section: Distress and Emotional Healthmentioning

confidence: 99%

Physical Activities and Distress among Participants of a Cancer Wellness Centre: A Community-Based Pilot Study

Leimanis

Fitzpatrick²

2014

Int J Phys Med Rehabil

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“…The majority of the available data come not from studies determining patients' syndromal or subsyndromal PTSD diagnoses, but from patient self-reports of traumatic symptoms found to be correlated with poor quality of life and/or impaired physical functioning (e.g., Diemling, Kahana, Bowman, & Schaefer, 2002;Jacobsen et al, 1998; for a review, see Kangas, Henry, & Bryant, 2002 (Gurevich et al, 2002;Kangas et al, 2002), only 8 studies used diagnostic interviews (e.g., SCID; First, Spitzer, Gibbon, & Williams, 1996). Across studies, 0 to 10 patients with PTSD were identified, for a total of 40 PTSD cases in the literature from over 700 patients assessed (Alter et al, 1996;Brewin, Watson, McCarthy, Hyman, & Dayson, 1998;Green et al, 1998;Kangas, Henry, & Bryant, 2005;Mehnert & Koch, 2007;Mundy et al, 2000;Palmer, Kagee, Coyne, & DeMichele, 2004;Pitman et al, 2001).…”

Section: Introductionmentioning

confidence: 99%

“…Along with the entry of baseline functioning, the analyses include potentially important cofactors (younger age, extent of treatment, and time since diagnosis) identified from cancer studies assessing PTSD symptom reports (e.g., Jacobsen et al, 1998;Green et al, 2000). The PTSD literature suggests a history of psychiatric disorder and trauma as important (see Brewin, Andrews, & Valentine, 2000, for a metaanalysis).…”

mentioning

confidence: 99%

PTSD diagnoses, subsyndromal symptoms, and comorbidities contribute to impairments for breast cancer survivors

Shelby

Golden-Kreutz

Andersen

2008

Journal of Traumatic Stress

117

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The clinical importance of posttraumatic stress disorder (PTSD) symptomatology for cancer patients is unclear. The association between the magnitude of cancer-related PTSD symptoms, comorbidity, and functioning is tested. Breast cancer patients (N = 74) were assessed at diagnosis/surgery, followed, and screened for cancer-related PTSD 18 months later. Participants then completed diagnostic interviews and PTSD (n = 12), subsyndromal PTSD (n = 5), and no symptom (n = 47) patient groups were identified. Posttraumatic stress disorder cases were distinguished by having experienced violent traumas and anxiety disorders predating cancer, whereas subsyndromal cases were not. Also, longitudinal data show that PTSD covarys with poorer functioning and lower quality of life among breast cancer survivors. Both PTSD and subsyndromal PTSD were associated with employment absenteeism and the seeking of mental health services.Studies of posttraumatic stress disorder (PTSD) in cancer patients find that diagnostic rates are low (3% to 14%), but symptomatology falling short of the diagnostic criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV; American Psychiatric Association [APA], 1994)-PTSD that is subsyndromal-may occur in upward of 50% of patients (Gurevich, Devins, & Rodin, 2002). How disabling subsyndromal PTSD may be for any individual is not fully known; however, the few data suggest that it is so. Stein, Walker, Hazen, and Forde (1997) using community survey data found that individuals with subsyndromal PTSD reported employment problems, social disruptions, and difficulties in the home. Similarly, Ciechanowski, Walker, Russo, Newman, and Katon (2004) found in a general survey of women in a health maintenance organization that quality of life was lower among those with subsyndromal PTSD compared to those with no symptoms. Finally, Marshall and colleagues (2001), using data from over 9,000 adults screened for anxiety disorders, reported that the presence of subsyndromal symptoms significantly raised the risk for suicidal ideation.It is not known if similar disruptions occur for cancer survivors. The majority of the available data come not from studies determining patients' syndromal or subsyndromal PTSD diagnoses, but from patient self-reports of traumatic symptoms found to be correlated with poor quality of life and/or impaired physical functioning (e.g., Diemling, Kahana, Bowman, & Schaefer, 2002;Jacobsen et al., 1998; for a review, see Kangas, Henry, & Bryant, 2002 (Gurevich et al., 2002;Kangas et al., 2002), only 8 studies used diagnostic interviews (e.g., SCID; First, Spitzer, Gibbon, & Williams, 1996). Across studies, 0 to 10 patients with PTSD were identified, for a total of 40 PTSD cases in the literature from over 700 patients assessed (Alter et al., 1996;Brewin, Watson, McCarthy, Hyman, & Dayson, 1998;Green et al., 1998;Kangas, Henry, & Bryant, 2005;Mehnert & Koch, 2007;Mundy et al., 2000;Palmer, Kagee, Coyne, & DeMichele, 2004;Pitman et al., 2001). Thus, a study ...

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“…4,5 Posttransplantation health-related quality of life is impaired by disease severity and previous transplantations. 6 A controlled study found no difference in quality of life or psychiatric outcomes between patients who underwent liver transplantation because of alcoholic liver disease and those who underwent liver transplantation because of other chronic liver diseases.…”

mentioning

confidence: 99%

The relevance of anxiety, depression, and coping in patients after liver transplantation

Nickel

Wünsch

Egle

et al. 2002

Liver Transplantation

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The aim of this study is to investigate the effects of anxiety, depression, and coping on quality of life in patients after liver transplantation. Patients were asked to fill out a postal survey. Two hundred thirty-six of 375 patients (63%) who entered the study returned the questionnaires, and 186 of these patients could be included in the assessment. Anxiety and depression were surveyed using the Hospital Anxiety and Depression Scale; health-related quality of life, using the 36-Item Short-Form Health Survey; and coping strategies, using the Freiburg Questionnaire on Coping With Illness. In terms of physical and mental dimensions of health-related quality of life, psychosocial factors are far more relevant in liver transplant recipients than purely somatic factors, such as the number of posttransplantation complications or length of hospital stay. Through multiple regression analysis, we were able to account for 51% of the variance in the physical dimension of health-related quality of life and 58% of the variance in the mental dimension. Physical factors of depression, age, and employment and mental factors of anxiety and depression were significant for predicting healthrelated quality of life after liver transplantation. Depressive coping, anxiety, and depression, as well as aspects of the social environment, contribute considerably to determine well-being and health-related quality of life of patients after liver transplantation. O ver the past 15 years, liver transplantation has proven to be the treatment of choice in patients with terminal liver disease. The 1-year survival rate is approximately 80%; after 8 years, 61% of patients are still alive. 1 From the physician's point of view, it is necessary to optimize therapy with immunosuppressants and minimize complications with medical treatment. Diabetes mellitus, malignancies, weight gain, and, particularly, non-Hodgkin's lymphomas have been observed, in addition to increased rates of hypertension. Furthermore, the likelihood of fractures increases after transplantation. 2,3 These associated diseases, along with the transplantation procedure itself and changes in the patient's surroundings, exert considerable influence on a patient's quality of life.Previous investigations into quality of life in transplant recipients focused primarily on the relation between medical treatment and transplantation, i.e., type of immunosuppression, duration and severity of illness, and course of the transplantation (revisions, retransplantation, rejection responses), in addition to effects of these factors on patients' quality of life. 4,5 Posttransplantation health-related quality of life is impaired by disease severity and previous transplantations. 6 A controlled study found no difference in quality of life or psychiatric outcomes between patients who underwent liver transplantation because of alcoholic liver disease and those who underwent liver transplantation because of other chronic liver diseases. 7 Previous results indicated that lung, heart, and liver transplant re...

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Posttraumatic Stress Disorder Symptoms After Bone Marrow Transplantation for Breast Cancer

Cited by 142 publications

References 16 publications

Physical Activities and Distress among Participants of a Cancer Wellness Centre: A Community-Based Pilot Study

Physical Activities and Distress among Participants of a Cancer Wellness Centre: A Community-Based Pilot Study

PTSD diagnoses, subsyndromal symptoms, and comorbidities contribute to impairments for breast cancer survivors

The relevance of anxiety, depression, and coping in patients after liver transplantation

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