Posttraumatic stress disorder and depression in heart transplantation recipients: the relationship with outcome and adherence to medical treatment

Favaro, Angela; Gerosa, Gino; Caforio, Alida L.P.; Volpe, Bruce T.; Rupolo, Giampietro; Zarneri, Deborah; Boscolo, Simone; Pavan, Chiara; Tenconi, Elena; d’Agostino, Chiara; Moz, Monica; Torregrossa, Gianluca; Feltrin, Giuseppe; Gambino, Antonio; Santonastaso, Paolo

doi:10.1016/j.genhosppsych.2010.10.001

Cited by 105 publications

(104 citation statements)

References 29 publications

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“…This is surprising given that 15% to 36% of patients with heart failure experience depression, 40,41 40% experience anxiety, 16 and 10% to 17% experience posttraumatic stress disorder. 42,43 Symptoms of depression and anxiety can be disabling 15 and are associated with an increased risk of declines in physical health, 16 mortality, higher medication costs, 15 noncompliance with treatment, malignancies, 44,45 and hospital readmissions. 8 The limited available evidence suggests that there may be a link between LVAD technology and the patient's psychological adjustment.…”

Section: Need For Assessing Pros In Lvad Patientsmentioning

confidence: 99%

Patient-Reported Outcomes in Left Ventricular Assist Device Therapy

Brouwers

Denollet

Jonge

et al. 2011

Circ: Heart Failure

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Patient-reported outcomes in left ventricular assist device therapyBrouwers, C.J.; Denollet, J.; de Jonge, N.; Caliskan, K.; Kealy, J.; Pedersen, S.S. General rightsCopyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.-Users may download and print one copy of any publication from the public portal for the purpose of private study or research -You may not further distribute the material or use it for any profit-making activity or commercial gain -You may freely distribute the URL identifying the publication in the public portal Take down policyIf you believe that this document breaches copyright, please contact us providing details, and we will remove access to the work immediately and investigate your claim. Background-Technological advancements of left ventricular assist devices (LVAD) have created today's potential for extending the lives of patients with end-stage heart failure. Few studies have examined the effect of LVAD therapy on patient-reported outcomes (PROs), such as health status, quality of life, and anxiety/depression, despite poor PROs predicting mortality and rehospitalization in patients with heart failure. In this systematic review, we provide an overview of available evidence on the impact of LVAD therapy on PROs and discuss recommendations for clinical research and practice. Methods and Results-A systematic literature search identified 16 quantitative studies with a sample size Ն10 (meanϮSD ageϭ50.1Ϯ12.6 years) that examined the impact of LVAD therapy on PROs using a quantitative approach. Initial evidence suggests an improvement in health status, anxiety, and depression in the first few months after LVAD implantation. However, PRO scores of patients receiving LVAD therapy are still lower for physical, social, and emotional functioning compared with transplant recipients. These studies had several methodological shortcomings, including the use of relatively small sample sizes, and only a paucity of studies focused on anxiety and depression. Conclusions-There is a paucity of studies on the patient perspective of LVAD therapy. To advance the field of LVAD research and to optimize the care of an increasingly growing population of patients receiving LVAD therapy, more well-designed large-scale studies are needed to further elucidate the impact of LVAD therapy on PROs. (Circ Heart Fail. 2011;4:714-723.)Key Words: left ventricular assist device Ⅲ patient-reported outcomes Ⅲ quality of life Ⅲ review

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Section: Need For Assessing Pros In Lvad Patientsmentioning

confidence: 99%

Patient-Reported Outcomes in Left Ventricular Assist Device Therapy

Brouwers

Denollet

Jonge

et al. 2011

Circ: Heart Failure

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“…A recent systematic review indicated that depression increases the risk of post-transplant mortality [190]. The presence of depression post-transplantation is frequent [191], equal to 41%. Grandi et al [192] reported that demoralization in combination with depresphases of instability, in the transition from hospital to home and in the terminal phases [139,145,[151][152][153].…”

Section: Strong Evidence • Behavioral Risk Factorsmentioning

confidence: 99%

“…To date, only a small number of studies have been dedicated to studying the psycho- Review sion predicted more acute rejection episodes in the 6-year period post-transplant than either variable considered independently. Major depression prior to heart transplantation is a risk factor for post-transplant malignancies and PTSD symptoms are a predictor of post-transplant poor adherence [191].…”

Section: Strong Evidence • Behavioral Risk Factorsmentioning

confidence: 99%

Best practice in psychological activities in cardiovascular prevention and rehabilitation: Position Paper

Angelino

Porta

Abatello

et al. 2018

Monaldi Arch Chest Dis

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Recent guidelines on cardiovascular disease prevention suggest multimodal behavioral interventions for psychosocial risk factors and referral for psychotherapy in the case of clinically significant symptoms of depression and anxiety overall. Accordingly, psychologists of the Italian Association for Cardiovascular Prevention, Rehabilitation and Epidemiology (GICR-IACPR) have reviewed the key components of psychological activities in cardiovascular prevention and rehabilitation (CPR). The aim of this study was to elaborate a position paper on the best practice in routine psychological activities in CPR based on efficacy, effectiveness and sustainability. The steps followed were: i) a review of the latest international guidelines and position papers; ii) analysis of the evidence-based literature; iii) a qualitative analysis of the psychological services operating in some reference Italian cardiac rehabilitation facilities; iv) classification of the psychological activities in CPR as low or high intensity based on the NICE Guidelines on psychological interventions on anxiety and depression. We confirm the existence of an association between depression, anxiety, social factors, stress, personality and illness onset/outcome and coronary heart disease. Evidence for an association between depression, social factors and disease outcome emerges particularly for chronic heart failure. Some positive psychological variables (e.g., optimism) are associated to illness outcome. Evidence is reported on the impact of psychological activities on 'new' conditions which are now indicated for cardiac rehabilitation: pulmonary hypertension, grown-up congenital heart, end-stage heart failure, implantable cardioverter-defribrillator and mechanical ventricular assist devices, frail and oldest-old patients, and end-of-life care. We also report evidence related to caregivers. The Panel divided evidence-based psychological interventions into: i) low intensity (counseling, psycho-education, self-care, self-management, telemedicine, self-help); or ii) high intensity (individual, couples and/or family and group psychotherapy, such as stress management). The results show that psychotherapy is mainly consisting of cognitive-behavior therapy, interpersonal therapy, and short-term psycho-dynamic therapy. The current data further refine the working tools available for psychological activities in CPR, giving clear directions about the choice of interventions, which should be evidence-based and have at least a minimum standard. This document provides a comprehensive update on new knowledge and new paths for psychologists working in the CPR settings.

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“…recipientų blogai laikėsi paskirto gydymo vaistais po širdies transplantacijos [13]. Tirti įvairūs veiksniai, susiję su šiuo paskirtu gydymo režimo nesilaikymu.…”

Section: Psichosocialinio Pažeidžiamumo Veiksniai Ir Transplantacijosunclassified

Potrauminio Streso Sindromas Bei Kiti Psichikos Sveikatos Sutrikimai Ir Organų Transplantacija

Miglinė

Miglinas

2014

Medicinos Teorija Ir Praktika

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Posttraumatic stress disorder and depression in heart transplantation recipients: the relationship with outcome and adherence to medical treatment

Cited by 105 publications

References 29 publications

Patient-Reported Outcomes in Left Ventricular Assist Device Therapy

Patient-Reported Outcomes in Left Ventricular Assist Device Therapy

Best practice in psychological activities in cardiovascular prevention and rehabilitation: Position Paper

Potrauminio Streso Sindromas Bei Kiti Psichikos Sveikatos Sutrikimai Ir Organų Transplantacija

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