Posttraumatic Stress and Posttraumatic Stress Disorder after Termination of Pregnancy and Reproductive Loss: A Systematic Review

Daugirdaitė, Viltė; Akker, Olga van den; Purewal, Satvinder

doi:10.1155/2015/646345

Cited by 72 publications

(65 citation statements)

References 94 publications

(127 reference statements)

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“…Our results indicate that there is no physiologic basis for delaying pregnancy attempt after a non-ectopic, non-molar, <20-week gestational age pregnancy loss. Recommendations to delay pregnancy attempts for at least 3–6 months among couples who are psychologically ready to begin trying (4, 26, 27) may be unwarranted and should be revisited.…”

Section: Discussionmentioning

confidence: 99%

Trying to Conceive After an Early Pregnancy Loss

Schliep

Mitchell

Mumford

et al. 2016

Obstetrics & Gynecology

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Objective To compare time to pregnancy and live birth among couples with varying intervals of pregnancy loss date to subsequent trying to conceive date. Methods In this secondary analysis of the Effects of Aspirin in Gestation and Reproduction trial, 1,083 women, aged 18–40 years with 1–2 prior early losses and whose last pregnancy outcome was a non-ectopic or non-molar loss, were included. Participants were actively followed for up to six menstrual cycles, and for women achieving pregnancy, until pregnancy outcome. We calculated intervals as start of trying to conceive date minus pregnancy loss date. Time to pregnancy was defined as start of trying to conceive until subsequent conception. Discrete Cox models, accounting for left truncation and right censoring, estimated fecundability odds ratios (OR) adjusting for age, race, BMI, education, and subfertility. While intervals were assessed prior to randomization and thus reasoned to have no relation with treatment assignment, additional adjustment for treatment was evaluated given that low-dose aspirin was previously shown to be predictive of time to pregnancy. Results Couples with a 0–3 month (n=765 [76.7%]) versus >3 month (n=233 [23.4%]) interval were more likely to achieve a live birth (53.2% versus 36.1%) with a significantly shorter time to pregnancy leading to live birth (median (IQR) 5 cycles (3, 8), adjusted fecundability OR: 1.71 [95% CI: 1.30, 2.25]). Additionally adjusting for low-dose aspirin treatment did not appreciably alter estimates. Conclusion Our study supports the hypothesis that there is no physiological evidence for delaying pregnancy attempt after an early loss.

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Section: Discussionmentioning

confidence: 99%

Trying to Conceive After an Early Pregnancy Loss

Schliep

Mitchell

Mumford

et al. 2016

Obstetrics & Gynecology

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“…all preterm births or very low birth weight babies) were excluded to avoid potential confounding with traumatic bereavement or perceived threat to the baby rather than self. It is also possible that different factors are associated with the development of PTSD after loss of a baby (Daugirdaite, van den Akker & Purewal, 2015).…”

Section: Inclusion and Exclusion Criteriamentioning

confidence: 99%

The aetiology of post-traumatic stress following childbirth: a meta-analysis and theoretical framework

et al. 2016

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“…Such defects are associated with less successful surgical repair compared with other forms of CHD and termination of pregnancy may be an appropriate form of management. Data suggest that psychological recovery after termination of pregnancy for fetal malformation is better the earlier the diagnosis is made.…”

Section: Introductionmentioning

confidence: 99%