Postsurgical thyroid remnant estimation by ^99mTc‐pertechnetate scintigraphy predicts radioiodine ablation effectiveness in patients with differentiated thyroid carcinoma

Abstract

The (⁹⁹m) Tc-pertechnetate scintigraphy is a simple and feasible tool to evaluate thyroid remnants and to predict radioiodine ablation results in patients with DTC.

Usefulness of 99mTc-pertechnetate whole body scan with neck and chest SPECT/CT for detection of post-surgical thyroid remnant and metastasis in differentiated thyroid cancer patients

“…The advantages of pertechnetate over 123 I are widely available, inexpensive with long enough half-life and easiness to prepare. There are some literatures demonstrating the roles of 99m Tc-pertechnetate in the detection of post-thyroidectomy remnant and/or metastasis [18][19][20][21][22]. From a previous study, the main problems of 99m Tc-pertechnetate are its low specificity, possibly due to lack of anatomical localization outside thyroid bed, and low negative predictive value [18].…”

Accuracy of Unstimulated Basal Serum Thyroglobulin Levels in Assessing the Completeness of Thyroidectomy

“…Recent studies have reported that sequential measurement of the basal serum Tg level is more effective in detecting the functional remnant of the thyroid gland after total excision [1, 2]. The 99 m Tc pertechnetate scintigraphy is a simple and feasible tool to evaluate the thyroid remnants after thyroidectomy [3]. The unstimulated baseline Tg values during TSH suppression in total thyroidectomy cases were below 0.5 ng/mL by 6 months postoperatively, and sensitive for absence of thyroid remnant [4].…”

Prediction of the success of thyroid remnant ablation using preablative 99mTc pertechnetate scintigraphy and postablative dual 131I scintigraphy

“…Several factors are known to affect the success of thyroid remnant ablation [6][7][8]. The extent of remnant thyroid tissue is one of the most important factors that influence the outcome of ablation [6,9]. Previous studies have demonstrated that a preablative diagnostic 131 I scan or thyroid bed uptake measurements can be used to evaluate the amount of thyroid remnant [7,[9][10][11][12].…”

“…The extent of remnant thyroid tissue is one of the most important factors that influence the outcome of ablation [6,9]. Previous studies have demonstrated that a preablative diagnostic 131 I scan or thyroid bed uptake measurements can be used to evaluate the amount of thyroid remnant [7,[9][10][11][12]. As a stunning effect can be caused by a diagnostic radioiodine scan using 131 I, 123 I, or 99m Tc pertechnetate scans are preferred for evaluating the amount of remnant thyroid tissue [9,[12][13][14].…”

“…Previous studies have demonstrated that a preablative diagnostic 131 I scan or thyroid bed uptake measurements can be used to evaluate the amount of thyroid remnant [7,[9][10][11][12]. As a stunning effect can be caused by a diagnostic radioiodine scan using 131 I, 123 I, or 99m Tc pertechnetate scans are preferred for evaluating the amount of remnant thyroid tissue [9,[12][13][14]. A previous study by Giovanella et al [9] revealed that 99m Tc pertechnetate scintigraphy before 131 I ablation can be used to evaluate for thyroid remnants and to predict the results of ablation in DTC patients.…”