Postruminal Delivery System for Amino Acids and Proteins in Cattle

Abstract

Sýkora T., M. Rabišková, J. Třináctý, D. Vetchý, A. Häring, P. Dvořák: Postruminal Delivery System for Amino Acids and Proteins in Cattle. Acta Vet. Brno 2007, 76: 547-552.The purpose of this experiment was to develop an effective postruminal transport system (PTS) with a high content of suitable vegetable proteins and amino acids. PTS serves for nutrient delivery to the abomasum and small intestine of dairy cows in order to increase the milk yield. Direct addition of proteins and amino acids to the diet is not useful as the ruminal microbes will utilize active substances before they reach absorption sites in the small intestine. PTS has several advantages, e.g. a possibility of the direct application in a food, low cost, and nutritional and therapeutical improvement. PTS consists of a core (pellets, small tablets) and a coating, which protects the core against the environment of rumen and enables to release the core content in the environment of abomasum and small intestine.Lenticular tablets -cores of PTS were prepared by wet granulation method and compression. Qualitative indicators of tablets (average weight, weight uniformity, hardness, friability, disintegration time) were determined according to valid Czech and European Pharmacopoeias. Cores were subsequently coated with several types of coating -ethylcellulose, stearic acid and pH sensitive polymer poly-(2-vinylpyridine-co-styren), alone or in combination of various rates.Nine samples of coated protein tablets exhibiting appropriate characteristics in vitro were prepared. The presence of the pH sensitive polymer at least in 10% concentration of the coating and the coating amount of 9.0 to 12.6% per tablet were necessary to ensure the requested PTS properties.

Encapsulation of bioactive compounds for the formulation of functional animal feeds: The biofortification of derivate foods

“…Coating materials include proteins (corn zein, wheat gluten, casein, gelatin, soy and whey proteins), polysaccharides (cellulose and other plant-based polymers), synthetic polymers (poly-2-vinylpyridine-co-styrene and polymethacrylate polymers) (Bribiesca et al, 2017;Temiz and Öztürk, 2018) and composites materials whereas the particle size varies from nano size to millimeter size. For example, particles diameter up to 6 mm has been suggested as optimum size of an encapsulated product for cattle (Sýkora et al, 2007). Based on the general values of rumen pH, 5.6 -7.0, coating materials with ability to degrade a pH below 5 could potentially survive rumen degradation and thus candidate for release in small the intestine formulations if they survive microbial degradation.…”

Detection of Cocaine and Amphetamine Regulated Transcript in the abomasum of slaughtered bulls with different daily body weight gains

“…This principally concerns those compounds that can be broken down through bacteria-aided digestion, such as proteins or methionine and lysine, a deficiency of which may limit production indicators of cattle (Sýkora et al 2007). Effective digestibility is also associated with the performance of the structures in the abdominal wall of ruminants.…”