Postreinforcement Pause Duration Varies Within a Session and With a Variable Response Requirement but Not as a Function of Prior Revolutions

Belke, Terry W.

doi:10.1007/bf03395757

Cited by 2 publications

(2 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Third, our aerobic exercise treatment was limited to a total of 6 hours (3 light: 3 dark). Although rats are more active in the dark cycle, Belke 63 demonstrated that when rats were restricted in the amount of time they had access to a running wheel, the light:dark period had no effect on the amount of time spent exercising. Future studies are needed to explore the effects of longer running periods, alone and in combination with other behavioral treatments, to investigate its potential beneficial role in forelimb recovery after TBI.…”

Section: Discussionmentioning

confidence: 99%

Combining Multiple Types of Motor Rehabilitation Enhances Skilled Forelimb Use Following Experimental Traumatic Brain Injury in Rats

Adkins

Ferguson

Lance

et al. 2015

Neurorehabil Neural Repair

View full text Add to dashboard Cite

Background Neuroplasticity and neurorehabilitation have been extensively studied in animal models of stroke to guide clinical rehabilitation of stroke patients. Similar studies focused on traumatic brain injury (TBI) are lacking. Objective The current study was designed to examine the effects of individual and combined rehabilitative approaches, previously shown to be beneficial following stroke, in an animal model of moderate/severe TBI, the controlled cortical impact (CCI). Methods Rats received a unilateral CCI, followed by reach training, voluntary exercise, or unimpaired forelimb constraint, alone or in combination. Forelimb function was assessed at different time points post-CCI by tests of skilled reaching, motor coordination, and asymmetrical limb use. Results Following CCI, skilled reaching and motor coordination were significantly enhanced by combinations of rehabilitation strategies, not by individual approaches. The return of symmetrical limb use benefited from forelimb constraint alone. None of the rehabilitation strategies affected the size of injury, suggesting that enhanced behavioral function was not a result of neuroprotection. Conclusions The current study has provided evidence that individual rehabilitation strategies shown to be beneficial in animal models of stroke are not similarly sufficient to enhance behavioral outcome in a model of TBI. Motor rehabilitation strategies for TBI patients may need to be more intense and varied. Future basic science studies exploring the underlying mechanisms of combined rehabilitation approaches in TBI as well as clinical studies comparing rehabilitation approaches for stroke versus TBI would prove fruitful.

show abstract

Section: Discussionmentioning

confidence: 99%

Combining Multiple Types of Motor Rehabilitation Enhances Skilled Forelimb Use Following Experimental Traumatic Brain Injury in Rats

Adkins

Ferguson

Lance

et al. 2015

Neurorehabil Neural Repair

View full text Add to dashboard Cite

show abstract

“…With few exceptions (Belke 2010(Belke , 2011Belke and Pierce 2009;Belke et al 2006;Collier and Hirsch 1971;Iversen 1993;Premack et al 1964), investigations of wheel running as a reinforcer have used interval and response-initiated interval schedules.…”

mentioning

confidence: 99%

Local Response Rates on Variable-Ratio Schedules of Wheel-Running Reinforcement are Relatively Invariant Compared to Sucrose

Belke

Kervin

et al. 2014

Psychol Rec

Self Cite

View full text Add to dashboard Cite

Responding on variable-ratio (VR) schedules of wheel-running and sucrose reinforcement was assessed using a within-session procedure. Six female Long Evans rats were exposed to schedules ranging from VR 3 to VR 40 in ascending and descending order within a session with sucrose (0.1 ml of 15 % solution) and wheel-running reinforcement (30 s). Within a session, 10 reinforcers were obtained on each schedule, with a 120 s inter-component interval between schedules. Results showed that local response rates generated by sucrose were higher and that the pattern of local response rates across the schedules differed substantively between reinforcer types. With sucrose, local rates decreased linearly as the ratio requirement increased. With wheel running, local rates did not differ except to decline on the highest ratio. Postreinforcement pauses were longer with wheel-running reinforcement and longer on the highest ratio when this ratio occurred at the end of a session. In contrast, wheel-running rates were lower on the smallest ratio schedule when this schedule occurred at the beginning of a session. The implications of the marked difference in local response rates across these schedules were discussed.

show abstract

Postreinforcement Pause Duration Varies Within a Session and With a Variable Response Requirement but Not as a Function of Prior Revolutions

Abstract: The current study examined the variables that influence postreinforcement pause (PRP)

Cited by 2 publications

References 34 publications

Combining Multiple Types of Motor Rehabilitation Enhances Skilled Forelimb Use Following Experimental Traumatic Brain Injury in Rats

Combining Multiple Types of Motor Rehabilitation Enhances Skilled Forelimb Use Following Experimental Traumatic Brain Injury in Rats

Local Response Rates on Variable-Ratio Schedules of Wheel-Running Reinforcement are Relatively Invariant Compared to Sucrose

Contact Info

Product

Resources

About