Postprandial Symptoms in Patients With Functional Dyspepsia and Irritable Bowel Syndrome: Relations to Ultrasound Measurements and Psychological Factors

Steinsvik, Elisabeth Kjelsvik; Valeur, Jørgen; Hausken, Trygve; Gilja, Odd Helge

doi:10.5056/jnm19072

Cited by 22 publications

(23 citation statements)

References 37 publications

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“…These measurements, as well as symptom scoring, were repeated at 10 and 20 min postprandially. Normal values for the UMAT are published in Steinsvik et al 16 In this paper, we used fasting antral area >5.4 cm 2 as a cutoff value for enlarged fasting antral area, based on mean plus two standard deviations from the healthy controls study.…”

Section: Methodsmentioning

confidence: 99%

Gastric function in diabetic gastroparesis assessed by ultrasound and scintigraphy

Steinsvik

Sangnes

Søfteland

et al. 2021

Neurogastroenterology Motil

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Background Gastroparesis is a severe diabetes complication characterized by delayed gastric emptying. We examined patients with symptoms of diabetic gastroparesis using gastric emptying scintigraphy and ultrasound drink test. The primary aim was to investigate how ultrasound could provide information about gastric motility features in diabetic gastroparesis. Material and methods We prospectively included 58 patients with diabetes (48 type 1) with symptoms of gastroparesis and 30 healthy controls. Patients were examined with ultrasound of the stomach in a seated position after drinking 500 ml low‐caloric meat soup, at the same time recording dyspeptic symptoms. The following day, they were examined with gastric emptying scintigraphy, defining gastroparesis as >10% retention after 4 h. Key Results We found motility disturbances in the proximal stomach measured by ultrasound in patients with diabetic gastroparesis. A linear mixed effects model including repeated ultrasound measurements revealed a slower decrease of the proximal stomach size in gastroparesis compared to healthy controls (p < 0.01), and the proximal diameter at 20 min was correlated to scintigraphy at 4 h (r = 0.510, p = 0.001). The antrum in patients with diabetic gastroparesis was twice as large compared to healthy controls (p = 0.009), and fasting antral size was correlated to gastric emptying scintigraphy (r = 0.329, p = 0.013). Both diabetes patients with and without gastroparesis had impaired accommodation (p = 0.011). Conclusions and Inferences On ultrasound, we found delayed reduction of proximal stomach size and impaired accommodation after a liquid meal in patients with gastroparesis, emphasizing the role of the proximal stomach. Furthermore, we found antral distention in gastroparesis patients.

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Section: Methodsmentioning

confidence: 99%

Gastric function in diabetic gastroparesis assessed by ultrasound and scintigraphy

Steinsvik

Sangnes

Søfteland

et al. 2021

Neurogastroenterology Motil

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“…However, in the construction of the database, we continued to use the Rome III to have homogeneous groups of patients. Finally, the present study lacks consideration of many lifestyle factors associated with OFGIDs as the response to food, 46 smocking, 47 and psychological status 48 ; these factors affect as well the severity of the diseases as the quality of life of these patients.…”

Section: Discussionmentioning

confidence: 98%

Characteristics of patients with overlap functional gastrointestinal disorders

Bouchoucha

Deutsch

Uong

et al. 2021

J of Gastro and Hepatol

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Background and Aim: Functional gastrointestinal disorders (FGIDs) are frequently overlapped. The present study was designed to (i) search the clinical differences between patients with single FGID and overlap FGIDs and (ii) define the most common FGIDs associations to identify homogenous subgroups of patients. Methods: A total of 3555 outpatients with FGID filled out the Rome III adult diagnostic questionnaire, Bristol stool form, and four 10-point Likert scales to report the severity of constipation, diarrhea, bloating, and abdominal pain. An unsupervised algorithm was used to estimate the number of groups directly from the data. A classification tree separated patients into different subgroups, according to FGIDs. Multinomial logistic regression was used to characterize the groups of patients with overlap disorders. Results: Patients reported 3.3 ± 1.9 FGIDs (range 1-10, median = 3); 736 reported only one FGID, while 2819 reported more than one FGID (3.8 ± 1.7). Patients with single FGID had higher body mass index (P < 0.001), never report irritable bowel syndrome (IBS), and rarely report fecal incontinence and anorectal pain (< 1% for each disorder). The non-supervised clustering of the 2819 patients with overlap FGIDs divided this population into 23 groups, including five groups associated with only one disorder (IBS-diarrhea, dysphagia, functional constipation, levator ani syndrome, and IBS-unspecified). Ten groups were related to two overlap disorders and eight groups to three or more disorders. Three disorders were not explicitly associated with a given group: IBS-mixed, proctalgia fugax, and nonspecific anorectal pain. Conclusion:Patients with FGID mostly report overlap disorders in a limited number of associations, each significantly associated with a few disorders.

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“…No difference in the rate of anxiety and depression was obtained between patients with organic and functional diseases of the digestive system. Many previous studies have focused on the psychosomatic status of patients with functional gastrointestinal disorders (FGIDs) such as irritable bowel syndrome (IBS) and functional dyspepsia (FD) [33][34][35][36]. It has been reported that in general hospitals, more than half of the patients with depression or anxiety visited the nonpsychiatric department for the first time.…”

Section: Discussionmentioning

confidence: 99%

Psychosomatic Disorders in Patients with Gastrointestinal Diseases: Single-Center Cross-Sectional Study of 1186 Inpatients

Feng

et al. 2021

Gastroenterology Research and Practice

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Objective. To investigate the prevalence of anxiety and depression in hospitalized patients in the Department of Gastroenterology and to explore the risk factors affecting psychosomatic conditions in patients with digestive disorders. Methods. Patients hospitalized with gastrointestinal diseases were enrolled by the Department of Gastroenterology of Xiangya Hospital of Central South University from November 2017 to June 2018 and completed a cross-sectional questionnaire survey. According to anxiety/nonanxiety, depression/nondepression, the subjects were divided into two groups, respectively, and the risk factors of anxiety/depression were analyzed. Results. A total of 1186 patients were included in this study. The overall detection rate was 20.74% for anxiety symptoms alone, 31.78% for depressive symptoms alone, 13.99% for both anxiety and depressive symptoms, and 38.53% for either depression or anxiety symptoms. The prevalence of anxiety symptoms was higher in female than in male patients and inversely correlated with levels of education. There was no significant difference in the detection rate of anxiety and depression between patients with functional and organic digestive diseases. Sleep quality and quality of life were inversely correlated with the severity of anxiety and depression. Notably, among the patients with abnormal psychological conditions, only 7.6% of them were willing to receive psychological treatment. Gender, sleep quality, and life quality are independent risk factors for anxiety and depression symptoms for inpatients with gastrointestinal diseases. Conclusion. Paying more attention to the education level, sleep quality, and quality of life in patients with gastrointestinal diseases will help doctors to identify the risk of psychological abnormalities and improve medical care.

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Postprandial Symptoms in Patients With Functional Dyspepsia and Irritable Bowel Syndrome: Relations to Ultrasound Measurements and Psychological Factors

Cited by 22 publications

References 37 publications

Gastric function in diabetic gastroparesis assessed by ultrasound and scintigraphy

Gastric function in diabetic gastroparesis assessed by ultrasound and scintigraphy

Characteristics of patients with overlap functional gastrointestinal disorders

Psychosomatic Disorders in Patients with Gastrointestinal Diseases: Single-Center Cross-Sectional Study of 1186 Inpatients

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