Postpartum Hemorrhage after Cesarean Delivery - Causes and Management Statistics of „Prof. Dr. Panait Sîrbu „ Hospital- Bucharest

Pană, D P; Carmen, Georgescu; Mitran, Mihai; Loredana, Mitran

doi:10.2478/arsm-2014-0006

Cited by 2 publications

(1 citation statement)

References 5 publications

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“…The management strategies include uterine massage, oxytocin, methylergometrine, and circulatory support with or without blood transfusion. It has been estimated that about 5% of cesarean delivery may experience PPH [ 7 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

Intravenous tranexamic acid vs. sublingual misoprostol in high-risk women for postpartum haemorrhage following cesarean delivery; a randomised clinical trial

Dawoud,

Al-Husseiny,

Helal

et al. 2023

BMC Pregnancy Childbirth

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Objective This study compares the effectiveness of administering sublingual misoprostol combined with oxytocin to that of IV tranexamic acid combined with oxytocin to reduce intra and post-operative blood loss in high-risk women for postpartum haemorrhage (PPH) following cesarean section (CS). Methods About 315 high-risk pregnant women undergoing CS participated in this trial. They were randomly assigned into three groups; tranexamic group, misoprostol group, and control group, according to the medication given in the operative theatre. All patients received oxytocin intraoperatively. They were assessed regarding intraoperative blood loss, the incidence of PPH, and the reduction in haemoglobin and hematocrit values. Results Both tranexamic and misoprostol groups had similar results in reducing intra and post-operative blood loss. However, the reduction in haemoglobin and hematocrit were significantly lower in tranexamic and misoprostol groups compared to the control group (-0.78 ± 0.57 vs. -0.83 ± 0.52 vs. -1.32 ± 0.57 gm/dl, P < 0.001 and − 3.05 ± 1.28 vs. -3.06 ± 1.13 vs. -4.94 ± 1.82%, P < 0.001 respectively). In addition, the estimated blood loss was significantly lower in the tranexamic and misoprostol groups compared to the control group (641.6 ± 271.9 vs. 617.9 ± 207.4 vs. 1002.4 ± 340.7 ml, P < 0.001). Conclusion Both tranexamic acid and misoprostol are equally capable of reducing blood loss, but the results were significantly better compared to using oxytocin alone in high-risk patients. Clinical Trial Registration Registered at www.clinicaltrials.govon07/10/2019 with registration number NCT04117243.

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Section: Introductionmentioning

confidence: 99%

Intravenous tranexamic acid vs. sublingual misoprostol in high-risk women for postpartum haemorrhage following cesarean delivery; a randomised clinical trial

Dawoud,

Al-Husseiny,

Helal

et al. 2023

BMC Pregnancy Childbirth

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Faktor Risiko Kejadian Atonia Uteri

Lestari

Mulawardhana

Utomo

2020

Pediomaternal Nurs. J.

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Introduction: Postpartum Hemorrhage is one of the main cause of maternal morbidity and mortality worlwide. Every 4 minutes one woman is estimated dead by this case. The cause of postpartum hemorrhage is known as ‘4 T’s’ (tone, tissue, trauma, and thrombin). Common aetiology of hemorrhage postpartum is uterine atony. Uterine atony can be caused by several risk factors . The aim of this study is to determine the correlation between advanced maternal age, grande multiparity, uterine overdistension, labour augmented, and prolonged labour as risk factors with the incidence of uterine atony.Methods: This study was an analysis of observational study with case-control design conducted at a tertiary hospital in Surabaya. The population was all medical record of postpartum women who had hemorrhage in 2016-2018. The case group was postpartum woman who had hemorrhage due to uterine atony and the control group due to other causes. The sample size of the case group was 37 respondents and the control group was 35 respondents, they were obtained through purposive sampling. The independent variables in this study was maternal age, parity, uterine overdistension, labour augmented, and prolonged labour; the dependent variable was uterine atony. Univariate analysis was used to describe respondent’s characteristic and bivariate analysis was used to determine the correlation between risk factors and the incidence of uterine atony. Fisher Exact was used to analyze the data with α= 0,05.Results: Fisher Exact showed there was correlation between uterine overdistension and uterine atony (p value=0,036; OR= 4,423; 95% CI 1,023-27,267) on the other hand it showed no correlation between maternal age, parity, augmented labour, and prolonged labour with uterine atony (p value >0,05).Conclusion: Increased awareness of pre-conceptual care and early detection of risk factors are needed to reduce the risk factors of the incidence of uterine atony especially in uterine overdistension.

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Postpartum Hemorrhage after Cesarean Delivery - Causes and Management Statistics of „Prof. Dr. Panait Sîrbu „ Hospital- Bucharest

Cited by 2 publications

References 5 publications

Intravenous tranexamic acid vs. sublingual misoprostol in high-risk women for postpartum haemorrhage following cesarean delivery; a randomised clinical trial

Intravenous tranexamic acid vs. sublingual misoprostol in high-risk women for postpartum haemorrhage following cesarean delivery; a randomised clinical trial

Faktor Risiko Kejadian Atonia Uteri

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