Postpartum Breast Cancer and Survival in Women With Germline BRCA Pathogenic Variants
Zhenzhen Zhang,
Shangyuan Ye,
Sarah M. Bernhardt
et al.
Abstract:ImportanceIn young-onset breast cancer (YOBC), a diagnosis within 5 to 10 years of childbirth is associated with increased mortality. Women with germline BRCA1/2 pathogenic variants (PVs) are more likely to be diagnosed with BC at younger ages, but the impact of childbirth on mortality is unknown.ObjectiveTo determine whether time between most recent childbirth and BC diagnosis is associated with mortality among patients with YOBC and germline BRCA1/2 PVs.Design, Setting, and ParticipantsThis prospective cohor… Show more
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