Postoperative Yanghe decoction regimen improves outcomes for idiopathic granulomatous mastitis

Zhang, Xing; Li, Jing; Hu, Xian-Jie

doi:10.1097/md.0000000000023136

Cited by 9 publications

(7 citation statements)

References 27 publications

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“…Most patients had a good outcome after treatment. There is also recent clinical research suggesting that traditional Chinese medicine is effective in treating mastitis, indicating the potential advantage of traditional Chinese medicine ( 25 , 26 ).…”

Section: Discussionmentioning

confidence: 99%

Classification of 27 Corynebacterium kroppenstedtii -Like Isolates Associated with Mastitis in China and Descriptions of C. parakroppenstedtii sp. nov. and C. pseudokroppenstedtii sp. nov

et al. 2022

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In this study, we characterized two novel species that were closely related to but hard to distinguish from C . kroppenstedtii by routine identification methods used in clinical laboratories. Since all 27 C. kroppenstedtii -like isolates were obtained from breast specimens of female patients with mastitis, they may be potential pathogens causing mastitis. We hope to perform further epidemiological investigation of these strains and explore their role in mastitis.

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Section: Discussionmentioning

confidence: 99%

Classification of 27 Corynebacterium kroppenstedtii -Like Isolates Associated with Mastitis in China and Descriptions of C. parakroppenstedtii sp. nov. and C. pseudokroppenstedtii sp. nov

et al. 2022

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“…[17] Combined with surgery, it can significantly shorten the treatment period and improve the surgical cure rate. [18] Overall, TCM has the effect of increasing the cure rate and decreasing the recurrence rate without obvious adverse reactions.…”

Section: Discussionmentioning

confidence: 99%

Clinical features and risk factors of bilateral granulomatous lobular mastitis

Ge,

Sun,

Feng

et al. 2024

Medicine

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Granulomatous lobular mastitis (GLM) is an idiopathic inflammatory breast disease that tends to recur on the same side. With the accumulation of clinical cases, it has been observed that GLM can also occur contralaterally. Currently, most studies on GLM focus on treatment methods and risk factors for ipsilateral recurrence, and there are few reports on bilateral GLM. The study aimed to summarize the clinical characteristics of patients with bilateral GLM by reviewing their clinical data, and to discuss the risk factors affecting the occurrence of bilateral GLM. A retrospective study of the medical records database of patients with GLM admitted between May 2019 and August 2022 was performed. Patients were divided into bilateral GLM group (bilateral GLM group) and unilateral GLM patients (unilateral GLM group). Demographic and clinical characteristics, treatment, and follow-up were collected and analyzed. In this study, by reviewing the clinical data of 59 cases of bilateral GLM, we found that the median time between the onset of bilateral GLM on both sides was 6.63 (0–18) months. Additionally, because of the simultaneous or interval onset on both sides, the duration of the disease was longer compared to unilateral cases. Regarding the history of external hospital treatment, it was found that about 57.63% of patients with bilateral GLM received 2 or more treatment modalities, with a higher involvement of herbal medicine. Meanwhile, by counting the clinical data of the 2 groups of patients with bilateral GLM and unilateral GLM, it was shown by univariate analysis that fertility, nipple development, absolute CD4 value, and CD4/CD8 ratio were associated with contralateral onset of GLM in both groups, with inverted nipple being an independent risk factor.

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“…Wang et al found that surgery after steroid treatment has a faster curative effect and a lower recurrence rate than steroid treatment alone ( 22 ). Zhang et al found that TCM YangHe decoction combined with surgical treatment had a higher cure rate and a lower recurrence rate than surgical treatment alone ( 23 ). Zuo et al also believed that the treatment of GLM with integrated traditional Chinese and Western medicine could improve the aesthetics of both breasts, thus it is worthy of clinical recommendation ( 24 ).…”

Section: Discussionmentioning

confidence: 99%

The Effectiveness of Traditional Chinese Medicine Combined With Surgery to Treat Granulomatous Mastitis: A Propensity-Matched Analysis

Sawuer

Sun

et al. 2022

Front. Oncol.

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PurposeThe etiology and pathology of granulomatous mastitis (GLM) are still unknown. Expert consensus on the treatment of GLM has not been developed. The objective of this study is to study the effectiveness of traditional Chinese medicine (TCM) combined with surgery in treating GLM.Materials and MethodsA retrospective cohort study was implemented at Longhua Hospital of Shanghai University of Traditional Chinese Medicine in China between September 2019 and August 2021. Female patients were included according to the propensity-score matching (PSM) method and balanced according to age and BMI. Patients with GLM diagnosed by pathology and a course of disease ≥ 6 months were included in this trial. Patients were divided into the TCM alone group or TCM + surgery group.ResultsIn total, 168 female patients were assessed and 102 patients were included in the study after PSM (51 in the TCM group and 51 in the TCM + surgery group). The average age of the patients was 32 years (21-47 years). There was no significant baseline characteristics difference between two groups after PSM. The suppuration rate in the TCM + surgery group was less than that in the TCM group (64.7% vs. 83.35%, P < 0.05), and the TCM + surgery group had a higher 9-month cure rate than the TCM group (86.3% vs. 52.9%, P < 0.05). The full course of disease in the TCM + surgery group was shorter than that in the TCM group (253.9 ± 117.3 days vs. 332.5 ± 111.6 days, P < 0.05).ConclusionsTCM combined with surgery can improve the cure rate and shorten the full course of GLM treatment, indicating surgery should be integrated in the clinical management of GLM.

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Postoperative Yanghe decoction regimen improves outcomes for idiopathic granulomatous mastitis

Cited by 9 publications

References 27 publications

Classification of 27 Corynebacterium kroppenstedtii -Like Isolates Associated with Mastitis in China and Descriptions of C. parakroppenstedtii sp. nov. and C. pseudokroppenstedtii sp. nov

Classification of 27 Corynebacterium kroppenstedtii -Like Isolates Associated with Mastitis in China and Descriptions of C. parakroppenstedtii sp. nov. and C. pseudokroppenstedtii sp. nov

Clinical features and risk factors of bilateral granulomatous lobular mastitis

The Effectiveness of Traditional Chinese Medicine Combined With Surgery to Treat Granulomatous Mastitis: A Propensity-Matched Analysis

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