Postoperative Surgical Site Infection After Spine Surgery: An Update From the Scoliosis Research Society (SRS) Morbidity and Mortality Database*

Shillingford, Jamal N.; Laratta, Joseph L.; Reddy, Hemant; Ha, Alex; Lehman, Ronald A.; Lenke, Lawrence G.; Fischer, Charla R.

doi:10.1016/j.jspd.2018.04.004

Cited by 36 publications

(33 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In this study, there was no statistically signi cant difference in the incidence of postoperative complications between the stable and unstable groups. However, we observed that the incidence rate of incision infection was higher than previously reported [23] . Also, the incidence of postoperative reduced gastrointestinal motility was higher.…”

Section: The Occurrence Of Complicationscontrasting

confidence: 81%

The effects of preoperative imaging stability studies on intraoperative correction, postoperative observation, and clinical efficacy of adult lumbar spondylolisthesis treatment

Jiang¹,

Liu²,

Zhang³

et al. 2020

Preprint

View full text Add to dashboard Cite

Background The aim of this study is to explore the use of preoperative imaging stability studies of adult lumbar spondylolisthesis and it's effects on intraoperative correction, postoperative observation, and clinical efficacy. Methods We retrospectively analyzed a total of 104 patients diagnosed with lumbar spondylolisthesis who underwent Posterior lumbar interbody fusion surgery between 2011 and 2014. The qualified patients were divided into two groups; group A (study/unstable group: 52 cases) and group B (control/stable group: 52 cases). Group A was further divided into group A1 (slip instability: 27 cases) and group A2 (angular instability: 25 cases). The preoperative lumbar sagittal plane translation distances and segmental angle of the preoperative lateral X-rays, hyperflexion X-rays, and hyperextension X-rays were measured and compared with their third-day postoperative lateral X-ray, and slip rate. The occurrences of intraoperative or postoperative complications, one-month postoperative follow-up data, including JOA, and VAS scores were access to evaluate the clinical efficacy of the treatment. Results Satisfactory postoperative radiographic correction was recorded in all groups. Better correction and correction was observed in group A1 patients and group B patients who used puller screws compared to those who used normal screws (P < 0.05). However, patients in group A2 who used normal pedicle screws had similar correction as those who used puller screws. The preoperative VAS scores showed that low back and lower extremity pain were higher in A1 and A2 groups compared to group B. However, they were lower one month postoperative. The preoperative JOA scores for the unstable groups (group A1 and A2) were lower than their stable counterpart but higher during the first month postoperative. Our analysis of postoperative complications also revealed no statistically significant difference between groups A1 and B, and groups A2, and B. Conclusions Preoperative imaging stability for adult lumbar spondylolisthesis does not affect intraoperative correction. The use of puller pedicle screws in patients with unstable or stable segmental slippage could achieve better correction and correction than with normal pedicle screws. The preoperative symptoms of patients with unstable segments were worse than their stable counterparts; however, their postoperative recovery was quicker in the first month postoperative.

show abstract

Section: The Occurrence Of Complicationscontrasting

confidence: 81%

The effects of preoperative imaging stability studies on intraoperative correction, postoperative observation, and clinical efficacy of adult lumbar spondylolisthesis treatment

Jiang¹,

Liu²,

Zhang³

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…Likewise, community-acquired spine infections (SI) are associated with enhanced morbidity; costs and prolonged hospital stay for the patients [1]. Most scientific papers are rather interested in the epidemiology of SI [2], occurring at 1% to 3% [2][3][4], rather than the modalities and outcomes of their treatment. Generally, literature on antibiotic regimens in SI is very sparse and strongly eminence-based (instead of basing on evidence).…”

Section: Background and Rationalementioning

confidence: 99%

Short post-surgical antibiotic therapy in spine infections - prospective, randomized, unblinded, non-inferiority trials (SASI Trials)

Betz

Uçkay

Schüpbach

et al. 2019

Preprint

View full text Add to dashboard Cite

Background: There are several open scientific questions regarding the optimal antibiotic treatment of spine infections (SI) with or without an implant. The duration of post-surgical antibiotic therapy is debated. Methods: We will perform and perform two unblinded randomized -controlled RCTs. We hypothesize that shorter durations of systemic antibiotic therapy after surgery for SI are non-inferior (10% margin, 80% power, ɑlpha 5%) to existing (long) treatment durations. The RCTs allocate the participants in two arms of 2 x 59 episodes each: 3 vs. 6 weeks of targeted post-surgical systemic antibiotic therapy for implant-free spine infections (two positive microbiological samples); or 6 vs. 12 weeks for implant-related spine infections. This equals a total of 236 adult SI episodes (randomization schemes 1:1) with a minimal follow-up of 12 months. All participants have a concomitant multidisciplinary surgical, re-educational, internist and infectious diseases care. We perform three interim analyses that are evaluated by an independent Study Data Monitoring Committee. Besides the primary outcome remission, we also assess adverse events of antibiotic therapy, changes of the patient’s nutritional status, total costs, functional scores, and the timely evolution of the (surgical) wounds. We define infection as the presence of local signs of inflammation (pus, wound discharge, calor, rubor, pain) together with microbiological evidence of the same pathogen(s) in at least two intraoperative samples; and remission as the absence of any clinical, laboratory and/or radiological evidence of (former or new) infection. Discussion: Provided that there is adequate surgical debridement, both RCTs enable to potentially prescribe less antibiotics during the therapy of SI; with potentially less adverse events and reduced overall costs. Trial registration: ClinicalTrial.gov NCT0408304. Registered on 6 th August 2019. Protocol version : 2 (5 th July 2019)

show abstract

“…Similarly, surgical site infection (SSI) after internal osteosynthesis for closed fracture has a reported incidence ranging from 0.5% to 10% [5,6,7,8], and up to 50% after open fractures [9]. In line with this figures, SSI following spine surgery occurs in 1% to 14% of patients, depending on the preoperative diagnosis and type of surgery [10,11].…”

mentioning

confidence: 92%

Local Antibacterial Implant Protection in Orthopedics and Trauma: What’s New?

Romanò¹,

Божкова

Artyukh

et al. 2019

Traumatology and Orthopedics of Russia

View full text Add to dashboard Cite

Current prophylactic and hygienic measures notwithstanding, implant-related infection remains among leading reasons for failure in orthopaedics and trauma surgery, resulting in extremely high social and economic costs. Various antibacterial coating technologies have been proven safe and effective both in preclinical and in clinical settings and able to reduce post-surgical infections up to 90%, depending on the type of the coating and on the experimental setup. In spite of this findings, the widespread use of these technologies is still limited by several factors. After reviewing the latest evidence on currently available antibacterial coatings, an algorithm is proposed to calculate the impact of the delayed introduction of these technologies in the clinical practice. When applied to joint arthroplasties, our calculator shows that each year of delay to implement an antibacterial coating, able to reduce post-surgical infection by 80% at a final user's cost price of €600, causes an estimated 35 200 new cases of periprosthetic joint infection in Europe and additional annual hospital costs of approximately €440 million. Faster and more affordable regulatory pathways for antibacterial coating technologies and an adequate reimbursement policy for their clinical use appear a feasible solution to mitigate the impact of implant-related infections and may benefit patients, healthcare systems, and related research. реферат несмотря на современные достижения профилактики и гигиены, имплант-ассоциированная инфекция остается одной из основных причин несостоятельных результатов ортопедических и травматологических вмешательств, что приводит к чрезвычайно высоким социальным и экономическим издержкам. Различные технологии антибактериального покрытия имплантатов зарекомендовали себя как безопасное и эффектив-

show abstract

Postoperative Surgical Site Infection After Spine Surgery: An Update From the Scoliosis Research Society (SRS) Morbidity and Mortality Database*

Cited by 36 publications

References 35 publications

The effects of preoperative imaging stability studies on intraoperative correction, postoperative observation, and clinical efficacy of adult lumbar spondylolisthesis treatment

The effects of preoperative imaging stability studies on intraoperative correction, postoperative observation, and clinical efficacy of adult lumbar spondylolisthesis treatment

Short post-surgical antibiotic therapy in spine infections - prospective, randomized, unblinded, non-inferiority trials (SASI Trials)

Local Antibacterial Implant Protection in Orthopedics and Trauma: What’s New?

Contact Info

Product

Resources

About