Postoperative Rhabdomyolysis Following Laparoscopic Gastric Bypass in the Morbidly Obese

Abstract

Hypothesis: Laparoscopic approaches for weight reduction in the morbidly obese have become common with more than 50000 bariatric surgical procedures being performed in 2001. The objective of this article is to raise awareness among surgeons of a new complication of rhabdomyolysis from this frequent procedure.

Acute Kidney Injury after Gastric Bypass Surgery

“…The use of HMG-CoA reductase inhibitors was not associated with AKI in our cohort. Although complications such as perioperative rhabdomyolysis have been reported (22,23), we found no association among use of these agents, rhabdomyolysis, and occurrence of AKI.…”

The Impact of Renal Function on Outcomes of Bariatric Surgery

“…70,71 However, renal risks are associated with bariatric surgery. Specifically, acute kidney injury, 72 nephrolithiasis, [73][74][75][76][77][78] hyperoxaluria, [79][80][81][82][83][84][85] oxalate nephropathy, 85,86 and rhabdomyolysis 87,88 have been reported and may negatively affect renal function after bariatric surgery.…”

Safety and efficacy of bariatric surgery: Longitudinal Assessment of Bariatric Surgery

“…In addition, there are several mechanisms by which obesity may independently and negatively impact renal function such as by adipogenic hormones that may have direct injurious actions on the kidney 39 . However, bariatric surgery itself has been associated with progressive renal disease through a variety of mechanisms 40 , and may also contribute to the development of renal calculi. For these reasons LABS-2 will measure renal function by serum creatinine and cystatin and urinary albumin and creatinine, and will assess the prevalence of diagnosed nephrolithiasis at baseline and follow-up.…”