Postoperative Renal Failure

Noor, Saira; Usmani, Ali

doi:10.1016/j.cger.2008.07.004

Cited by 23 publications

(8 citation statements)

References 49 publications

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“…15,[17][18][19] In our study, age, male gender, history of chronic kidney disease, previous coronary revascularization, and increasing number of comorbidities were significantly associated with an increased risk of AKI, whereas after multivariable adjustment, only lower eGFR level remained as an independent predictor, similar to some other previous studies. [20][21][22][23] In our view, despite this finding, previous identification of other risk factors apart from low eGFR warrants further studies with different patient populations to better delineate the role of lower eGFR as a sole predictor of AKI.…”

Section: Discussionsupporting

confidence: 78%

Risk Factors for Acute Kidney Injury After Hip Fracture Surgery in the Elderly Individuals

Uluçay¹,

Eren²,

Kaspar

et al. 2012

Geriatr Orthop Surg Rehabil

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Objective: We aimed to evaluate possible risk factors assocıated wıth acute kidney injury (AKI) after hip fracture surgery in the elderly individuals. Design: Level II diagnostic study, evidence obtained from prospective cohort study from 1 center with level 2, and 3 patients. Patients: A total of 165 patients (>65 years) with femoral neck fracture were enrolled in this prospective study between 2007 and 2010. Two patients were dropped for inadequate laboratory follow-up data. Patients with kidney failure or renal replacement therapy (RRT) history or AKI at admission were excluded. Intervention: Nephrology consultation was obtained from all patients at admission. All patients had undergone bipolar cemented hip arthroplasty that was performed by the same surgical team in all patients within 24 hours of fracture and admission under the same protocol. Main Outcome Measurements: Serum creatinine (SCr), urine output, and complete blood counts were evaluated at baseline and daily basis thereafter. The AKI was defined based on Acute Kidney Injury Network classification. Hospital charges were converted from Turkish Liras to US dollars and rounded. Results: Among 163 patients, AKI occurred in 25 (15.3%) patients, all within the first 48 postoperative hours. Three (1.8%) patients required RRT. Baseline SCr levels were restored within 4.84 + 1.34 days on average (3-8 days). No patient required RRT after discharge. The mean hospital stay was 3 days (2-6 days) longer and the hospital charge was 2500 US$ higher for the patients with AKI. After multivariable adjustment, only lower estimated glomerular filtration rate levels (odds ratio 0.945, 95%confidence interval 0.92-0.96) emerged as an independent predictor for AKI. Conclusion: The AKI represents a frequent complication after hip fracture surgery associated with longer hospital stay and higher treatment costs with increased morbidity. Our results show baseline renal function is an independent predictor of AKI.

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Section: Discussionsupporting

confidence: 78%

Risk Factors for Acute Kidney Injury After Hip Fracture Surgery in the Elderly Individuals

Uluçay¹,

Eren²,

Kaspar

et al. 2012

Geriatr Orthop Surg Rehabil

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“…Some other studies demonstrated that preoperative factors and intraoperative factors of PO-AKI included advancing age, sepsis, hepatic failure, and hypovolemia. 3,27 However, we did not find such factors were related to poor prognosis in our patients. Since the diagnosing criteria of AKI/ARF were not unanimous between the literature and ours, the risk factors might be different accordingly.…”

Section: Discussioncontrasting

confidence: 42%

“…2 The mortality rate of PO-AKI is estimated to be more than 50%. 3 However, few studies have been published focusing on Chinese patients with PO-AKI. In this study, we investigate the clinical characteristics of Chinese patients with PO-AKI and survival rate in our patients in order to further study the disease.…”

Section: Introductionmentioning

confidence: 99%

Analyzing Chinese Patients with Post-Operative Acute Kidney Injury

et al. 2011

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Background: To investigate clinical characteristics and risk factors of Chinese patients with post-operative acute kidney injury (PO-AKI). Methods: Patients with PO-AKI in Ruijin Hospital from December 1997 to December 2005 were retrospectively studied. Results: Patients' mean age was 62.2 ± 18.1 years. There were 111 males and 57 females. The mean serum creatinine at diagnosis was 370.41 ± 320.92 µmol/L and the mean estimated glomerular filtration rate was 33.56 ± 24.24 mL/min. For the outcome of the patients, 38 died and the mortality rate was 22.6%. There were 17 patients (10.1%) with Acute Dialysis Quality Initiative-RIFLE (risk-injury-failure-loss-end classification) phase R, 21 (12.5%) with phase I, and 130 (77.4%) with phase F. There was no significant difference in mortality regarding patients who underwent different types of surgeries. For the risk factors related to PO-AKI, acute tubular necrosis (ATN) increased relative risk of mortality PO-AKI (odds ratio = 7.089, 95% confidence interval = 2.069-24.288, p < 0.001). Multivariate regression models showed that ATN had a positive correlation with mortality of PO-AKI. Conclusions: PO-AKI is one of the most common causes of AKI in patients who underwent operations. Special attention should be paid to risk factors related to PO-AKI in order to improve prognosis.

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“…Because of the combination of low blood flow and the high metabolic demand of the medulla relative to the cortex, acute tubular necrosis is considered the commonest cause of postoperative AKI and is primarily a result of hypoxic damage to the medulla. 34 If hypovolemia continues, the medulla may become more vulnerable to hypoxic damage.…”

Section: Discussionmentioning

confidence: 99%

Perioperative risk factors for acute kidney injury after liver resection surgery: an historical cohort study

Tomozawa

Ishikawa

Shiota

et al. 2015

Can J Anesth/J Can Anesth

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Perioperative risk factors for AKI after liver resection surgery are similar to those established for other surgical procedures. Further studies are needed to establish causality and to determine whether interventions on modifiable risk factors can reduce the incidence of postoperative AKI and improve patient outcome. This study was registered at the University Hospital Medical Information Network (UMIN) Center (UMIN 000008089).

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Postoperative Renal Failure

Cited by 23 publications

References 49 publications

Risk Factors for Acute Kidney Injury After Hip Fracture Surgery in the Elderly Individuals

Risk Factors for Acute Kidney Injury After Hip Fracture Surgery in the Elderly Individuals

Analyzing Chinese Patients with Post-Operative Acute Kidney Injury

Perioperative risk factors for acute kidney injury after liver resection surgery: an historical cohort study

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