Editor's key points † This study investigates the risk factors for reintubation in post-anaesthetic care units related to anaesthetic processes. † Risk factors were age ,1 yr, chronic pulmonary disease, preoperative hypoalbuminaemia and renal insufficiency, head and neck surgery, airway surgery, cardiothoracic surgery, cardiac catheterization, emergency case, duration of operation more than 3 h, ASA physical status III, and the use of certain neuromuscular blocking agents. Background. Risk factors for reintubation in post-anaesthetic care units related to anaesthetic processes have not previously been reported. Our goal was to identify risk factors for reintubation in general surgical patients. Methods. A time-matched, case-control study was conducted on anaesthetic patients between 2001 and 2011. One hundred and sixty-four reintubated patients were compared with 656 randomly selected controls. Results. Independent risk factors for reintubation were age ,1 yr vs age 30-49 yr [odds ratio (OR)¼16.4, 95% confidence interval (CI)¼5.7-47.7], chronic pulmonary disease (OR¼2.1, CI¼1.1-4.0), preoperative hypoalbuminaemia (OR¼4.9, CI¼2.4 -10), creatinine clearance ,24 vs .60 (OR¼4.1, CI¼1.2-13.4), emergency case (OR¼1.8, CI¼1.0-3.1), operative time .3 vs ,1 h (OR¼3.0, CI¼1.5 -6.2), airway surgery (OR¼32.2, CI¼13.6 -76), head and neck surgery (OR¼3.4, CI¼1.8 -6.2), cardiac surgery (OR¼3.8, CI¼1.1 -13.4), thoracic surgery (OR¼6.3, CI¼1.9-21.2), cardiac catheterization (OR¼2.5, CI¼1.1 -5.5), ASA physical status III (OR¼3.8, CI¼1.4-10), and the use of certain types of neuromuscular blocking agent (P,0.001). Conclusions. Age ,1 yr, chronic pulmonary disease, preoperative hypoalbuminaemia, and renal insufficiency were patient factors for reintubation. Emergency case, head and neck, cardiothoracic and airway surgery, and operative time .3 h were operative factors, while certain neuromuscular blocking agents and ASA physical status III were anaesthetic factors for reintubation.
ParticipantsThe anaesthetic database included all patients who were serviced by anaesthetists either inside or outside the operating theatres. The database consisted of two parts. The first part contained preoperative data and intraoperative data which were entered into the database upon admission to the PACU by the anaesthetists involved in the patient's intraoperative care. The second part consisted of postoperative