Postoperative reflux alkali gastritis and esophagitis

Mackman, Sanford; Lemmer, Kenneth E.; Morrissey, John F.

doi:10.1016/0002-9610(71)90048-1

Cited by 28 publications

(8 citation statements)

References 11 publications

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“…The pyloric region prevents duodenal juice from refluxing into the stomach. Distal gastrectomy for stomach cancer is accompanied by gastroesophageal reflux disease (GERD), [9][10][11][12] because dissection of the lymph nodes around the cardia causes a collapse of the reflux-prevention mechanism of the lower esophageal cardia. GERD is generally defined as "a condition in which the reflux of gastric juice into the esophagus causes histological changes on the mucosa of the lower esophagus," or "a condition in which stimulation on the mucosa of the esophagus Fig.…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of Roux-en-Y Reconstruction After Distal Gastrectomy Based on an Assessment of Biliary Kinetics

Shinoto¹,

Ochiai²,

Suzuki³

et al. 2003

Surgery Today

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Section: Discussionmentioning

confidence: 99%

Effectiveness of Roux-en-Y Reconstruction After Distal Gastrectomy Based on an Assessment of Biliary Kinetics

Shinoto¹,

Ochiai²,

Suzuki³

et al. 2003

Surgery Today

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“…A reflux of bile into the stomach has also been observed in patients with gallbladder disease who have not undergone surgical treatment [20]. Presence of bile in the stomach is considered the cause of impairment to the gastric mucosa, as has been observed after surgery with gastric resection [21][22][23][24] and cholecystectomy [15,[25][26][27]. A greater frequency of biliary gastritis is also found in patients with cholelithiasis [15][16][17][18][19][20][21][22][23][24][25].…”

Section: Discussionmentioning

confidence: 99%

Gallstones and gastric cancer: A matched case‐control study

et al. 1986

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A matched case‐control study was carried out in order to verify the association of gastric neoplasms and lithiasic biliary disease and to clarify the nature of this association in 157 patients operated on for gastric cancer. Each patient was examined for previous cholecystectomy. Concomitant cholelithiasis was identified by ultrasonographic and intraoperative exploration. A statistically significant incidence of concomitant cholelithiasis (p<0.01) was found in patients affected by cancer of the antropyloric region (27% versus 11.7%), in female patients (24.7% versus 11.8%, p<0.05), and in patients over the age of 65 (32.2% versus 17.2%, p<0.05). No association with cholecystectomy was revealed in any of the cases. On the basis of these results, it may be concluded that the association found is not to be attributed to well‐known risk factors that are common to both diseases or to alterations in the bile composition caused by lithiasic disease. It appears that cholecystectomy has a protective effect as regards the increased risk of gastric cancer in patients with cholelithiasis.

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“…In contrast, R-Y stasis syndrome, which occurs occasionally during the early postoperative period, is one of the major complications of R-Y reconstruction [9][10][11]. Most surgeons choose a reconstruction procedure according to personal preferences or degree of experience.…”

Section: Introductionmentioning

confidence: 99%

A comparison of postoperative quality of life and dysfunction after Billroth I and Roux-en-Y reconstruction following distal gastrectomy for gastric cancer: results from a multi-institutional RCT

et al. 2011

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Background Both Billroth I (B-I) and Roux-en-Y (R-Y) reconstructions are commonly performed as standard procedures, but it has yet to be determined which reconstruction is better for patients. A randomized prospective phase II trial with body weight loss at 1 year after surgery as a primary endpoint was performed to address this issue. The current report delivers data on the quality of life and degree of postoperative dysfunction, which were the secondary endpoints of this study.Methods Gastric cancer patients who underwent distal gastrectomy were intraoperatively randomized to B-I or R-Y. Postsurgical QOL was evaluated using the EORTC QLQ-C30 and DAUGS 20. Results Between August 2005 and December 2008, 332 patients were enrolled in a randomized trial comparing B-I versus R-Y. A mail survey questionnaire sent to 327 patients was completed by 268 (86.2%) of them. EORTC QLQ-C30 scores were as follows: global health status was similar in each group (B-I 73.5 ± 18.8, R-Y 73.2 ± 20.2, p = 0.87). Scores of five functional scales were also similar. Only the dyspnea symptom scale showed superior results for R-Y than for B-I (B-I 13.6 ± 17.9, R-Y 8.6 ± 16.3, p = 0.02). With respect to DAUGS 20, the total score did not differ significantly between the R-Y and B-I groups (24.8 vs. 23.6, p = 0.41). Only reflux symptoms were significantly worse for B-I than for R-Y (0.7 ± 0.6 vs. 0.5 ± 0.6, p = 0.01). Conclusions The B-I and R-Y techniques were generally equivalent in terms of postoperative QOL and dysfunction. Both procedures seem acceptable as standard reconstructions after distal gastrectomy with regard to postoperative QOL and dysfunction.

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Postoperative reflux alkali gastritis and esophagitis

Cited by 28 publications

References 11 publications

Effectiveness of Roux-en-Y Reconstruction After Distal Gastrectomy Based on an Assessment of Biliary Kinetics

Effectiveness of Roux-en-Y Reconstruction After Distal Gastrectomy Based on an Assessment of Biliary Kinetics

Gallstones and gastric cancer: A matched case‐control study

A comparison of postoperative quality of life and dysfunction after Billroth I and Roux-en-Y reconstruction following distal gastrectomy for gastric cancer: results from a multi-institutional RCT

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