Postoperative Pulmonary Embolism After Hospital Discharge

Huber, Olivier

doi:10.1001/archsurg.1992.01420030076014

Cited by 272 publications

(131 citation statements)

References 6 publications

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“…Miscellaneous condition 117 unknown cause that occurs within 3 months of surgery is considered to be the result of PE [5,11,33,35]. We confirmed the fatal PE, if present, from the death certificate.…”

Section: Sequelae Of Hip Infection 87mentioning

confidence: 56%

“…Moreover, the incidence of imaging-confirmed asymptomatic DVT and PE after THA without thromboprophylaxis reportedly ranges from 40% to 79% and from 7% to 30%, respectively [6,8,10,20]. Owing to such high incidences in western countries, the American Academy of Orthopaedic Surgeons (AAOS) [11], the American College of Chest Physicians (ACCP) [10], and the National Institute for Health and Clinical Excellence (NICE) [12], recommended routine use of thromboprophylactic agents including aspirin, low-molecular-weight heparin, and warfarin for patients undergoing THA. However, these agents expose patients to an 1.5-fold to threefold increased risk of bleeding complications including substantial bleeding or hematomas at the operative site and fatal bleeding at a nonoperative site such as the intestine [4,29].…”

Section: Introductionmentioning

confidence: 99%

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Deep Venous Thrombosis and Pulmonary Embolism are Uncommon in East Asian Patients after Total Hip Arthroplasty

Kang

Lee

Kim

et al. 2011

Clinical Orthopaedics &Amp; Related Research

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Background In Western countries, deep vein thrombosis (DVT) and pulmonary embolism (PE), are relatively common after THA and many surgeons recommend routine pharmacologic thromboprophylaxis. There is some suggestion in the literature that the incidences of DVT and PE may be lower in East Asian patients. Therefore, it would be important to establish the incidences in a large number of East Asian patients who did not receive pharmacologic thromboprophylaxis.Purpose We therefore determined the incidence of DVT and PE and evaluated the associated risk factors in a series of East Asian patients who underwent primary THA without pharmacologic prophylaxis. Methods We retrospectively evaluated all 861 patients who underwent 992 elective primary THAs from May 2003 to December 2009. We identified patients with symptomatic DVT, symptomatic PE, and fatal PE. For potential risk factors we considered age, gender, body mass index (BMI), administration of aspirin, type of anesthesia, operation time, approach, simultaneous bilateral THAs, and duration of immobilization between symptomatic and asymptomatic patients. Results We identified eight patients with symptomatic DVT, one of whom also had a symptomatic PE; there were no cases of fatal PE. The incidences of fatal PE, symptomatic PE, and symptomatic DVT were 0 %, 0

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Section: Sequelae Of Hip Infection 87mentioning

confidence: 56%

Section: Introductionmentioning

confidence: 99%

Deep Venous Thrombosis and Pulmonary Embolism are Uncommon in East Asian Patients after Total Hip Arthroplasty

Kang

Lee

Kim

et al. 2011

Clinical Orthopaedics &Amp; Related Research

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“…At the time of the survey (July-November 2001) there was no published evidence to support prolonged prophylaxis, although the risk of thromboembolism remains high in the month following major surgery [12]. A recently published study shows that thromboprophylaxis with LMWH for 4 weeks after surgery for abdominal or pelvic cancer significantly reduced the incidence of thrombosis, compared with treatment for just 1 week postsurgery [13].…”

Section: Venous Thrombosis In Cancer Patientsmentioning

confidence: 99%

Venous Thrombosis in Cancer Patients: Insights from the FRONTLINE Survey

et al. 2003

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Background. Venous thromboembolism (VTE) is a common complication in cancer patients and a significant cause of morbidity and mortality. However, little information is available on oncologists' perceptions of the risk of VTE and its management. The Fundamental Research in Oncology and Thrombosis (FRONTLINE) study is the first comprehensive global survey of thrombosis and cancer. The study was designed to collect data on the perceived risk and patterns of practice with regard to VTE in cancer patients undergoing surgical and medical management of their malignancy and to provide information on international and regional practice patterns, allowing for the design of research studies to answer the concerns of practicing clinicians.Methods. Literature reviews were performed to provide a current evidence base against which to compare the findings, and a survey was developed under the guidance of an advisory board. A paper-based replypaid questionnaire was distributed globally between July and November 2001 to clinicians involved in cancer care and was made available on a dedicated website.Findings. A total of 3,891 completed responses were available for analysis. Brain and pancreatic tumors were considered to carry a high risk for VTE, and 80% of respondents considered the use of central venous lines to be associated with a high risk of VTE. Marked differences were seen in the use of thromboprophylaxis for

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“…Studies of Western populations have shown that DVT rates range from 15% to 30% for cancer patients not receiving thromboembolic prophylaxis, and a meta-analysis by Colditz et al estimated fatal PE rates of 0.1%-0.8% (39,40). Colorectal surgery is associated with a specific high risk of postoperative thromboembolic complications relative to other general surgery (41)(42)(43). The incidences of DVT and PE in colorectal cancer surgery patients who do not receive thromboembolic prophylaxis are approximately 40% and 5%, respectively (42)(43).…”

Section: Vte In Cancer Patientsmentioning

confidence: 99%