Postoperative neuropsychological change and its underlying mechanism in patients undergoing coronary artery bypass grafting

The effect of music intervention in stress response to cardiac surgery in a randomized clinical trial

“…1 Cortisol is an important indicator of the activity of stress response, and the degree of surgical trauma is believed to correlate to the concentration of cortisol. 3 Increased cortisol levels can be seen in patients who have undergone CABG with a peak occurring in the immediate postoperative period, around the time of extubation. 4 Health care personnel are responsible for establishing a healing environment for the patient, an environment that reduces stress.…”

Depression, disability, and quality of life after off-pump coronary artery bypass grafting: A prospective 9-month follow-up study

“…undergoing CABG and did not include patients undergoing elective CABG, as in other studies, in which the prevalence of presurgical depression was as low as 28.1%. 7,16 These factors may explain the high rates of depression at baseline in this population. This study aimed to observe the effect of OPCABG on mood, disability, and QOL in the general population.…”

“…18 One possible explanation is that this study did not exclude patients previously known to have mood disorders, severe metabolic and endocrine disorders, or previous CABG, as was done in prior studies. 5,16,34 Our patient population consisted of only in-hospital patients The QOL scale shows an initial decrease from baseline and then a steady improvement to above baseline at 9 months. The SDS shows maximum disability occurring 1 month postoperatively but then returning to baseline at 9 months.…”

Brain damage and cardiopulmonary bypass: is there really any association?

“…Although the current literature search found no further systematic reviews and meta-analyses, three RCTs comparing the cognitive outcome in patients undergoing on-and off-pump CABG surgery were identified 18,[22][23][24] . One RCT had been published after completion of the last review and two were not identified by the previous literature search 18,[22][23][24] . One study, the Randomized On/Off Bypass (ROOBY) trial reported cognitive outcome in duplicate publications, once as a summary along with other clinical outcomes by Shroyer and colleagues (2009) and once as a more detailed report on cognition by Kozora and colleagues (2010) 18,24 .…”