Postoperative medical treatment of lower urinary tract symptoms after benign prostatic hyperplasia surgery. Are we underestimating the problem?

Abstract

Purpose of review The aim of this study was to determine whether well timed start of medical and surgical treatment of benign prostatic obstruction (BPO) influences the treatment's effectiveness and thus the patients’ overall functional outcomes and quality of life. Recent findings Pharmacological therapy even in high-volume (>80 cm3) BPH typically begins with α-blockers sole and only subsequently are 5ARI added. Several studies showed that acute urinary retention (AUR) developed more frequently in men who suffered severe lower urinary tract symptoms (LUTS) and who did not start combination therapy immediately. Moreover, there are no strict criteria which determine the right time for performing surgery in patients with mild and moderate LUTS, especially when pharmacological therapy fails. However, sometimes, the surgery does not eliminate all the symptoms, as it deals effectively with BPO, but does not treat an overactive bladder. Also, data show that surgery should be performed as soon as possible and be more radical after the first episode of AUR. Summary A combination of α-blockers and 5ARI makes for a good starting point where the treatment of high volume BPH is concerned. Ideally, surgery should be performed immediately or as soon as possible in patients with the first episode of AUR and ‘anatomic’ BPH tissue removal is preferable (dissection of tissue along the prostate capsule to remove its maximum volume).

Application of Urethral Contrast Computed Tomography Three-Dimensional Imaging in the Postoperative Assessment of Prostate Hyperplasia

“…Following TURP, some patients continue to exhibit minimal improvement in LUTS, which may be attributed to a variety of factors ( Chapple & Osman, 2022 ; Chen et al, 2019 ; Khavari et al, 2019 ; Sagen et al, 2020 ; Spivak et al, 2021 ). In some cases, LUTS may not be solely caused by BOO, making preoperative confirmation of BOO necessary.…”

Opportunities to increase early diagnostics and treatment compliance of BPH progression.

“…Are we underestimating the problem? » в которой представлены данные, свидетельствующие о необходимости раннего начала контроля над симптомами нарушения функции нижних мочевых путей [23]. Нами показано, что, исходя из полученных данных, можно утверждать, что более, чем половине мужчин, пришедших на профосмотр, требовалось медикаментозное лечение, но при этом они его не получали и к урологу не обращались и никаких профилактических и лечебных мер ими не использовалось!…”