Postoperative Infection With Pseudomonas Aeruginosa in an Eye Hospital

Control of Infection in Ophthalmic Surgery

“…But after intraocular operations, sepsis is nearly always very serious; in almost every case there is a real possibility that the eye will be lost. Thus, in a series of 22 infections (Allen & Mangiaracine 1964), evisceration of the eye was necessary in 11 and useful vision was lost in a further 7; in the Birmingham outbreak 15 infections led to the loss of 6 eyes (Ayliffe et al 1966).…”

Control of Infection in Ophthalmic Surgery

“…But after intraocular operations, sepsis is nearly always very serious; in almost every case there is a real possibility that the eye will be lost. Thus, in a series of 22 infections (Allen & Mangiaracine 1964), evisceration of the eye was necessary in 11 and useful vision was lost in a further 7; in the Birmingham outbreak 15 infections led to the loss of 6 eyes (Ayliffe et al 1966).…”

Alcaligenes xylosoxidans Endophthalmitis Following Phacoemulsification and Intraocular Lens Implantation

“…Several phenotypical methods have been employed in previous studies to identify similarities between bacterial infections, including antimicrobial susceptibility profiles 12,13 or phage, pyocin, and serological typing. 11 Cruciani et al were the first to use genotyping (pulsefield gel electrophoresis) as a means of correlating samples of three strains of P. aeruginosa taken from (1) patients with endophthalmitis following cataract surgery who had been operated on during different days and (2) phacoemulsifier internal tubing. 6 Previous pulsed-field gel electrophoresis tests for Alcaligenes used XbaI, SpeI, or DraI as restriction endonucleases.…”

“…Several reports of clustered endophthalmitis outbreaks following cataract surgery have been published, including series of patients who were operated on during the same day and infected by different bacteria 4 and series of patients operated on during different days and infected by the same bacteria. 6 The most frequently cited bacterium in these studies has been P. aeruginosa, 3,4,6,7,[11][12][13]15 but other bacteria such as Staphylococcus, 4 Acremonium kiliense, 8 and Empedobacter brevis 5 are regularly incriminated. To date, our series is the first to report an endophthalmitis series involving Alcaligenes.…”

Bacterial Contamination of Drops and Dropper Tips of In‐use Multidose Eye Drop Bottles

“…Conflicting views have been presented regarding the frequency and importance of microbial contamination of eye drops. Thus bacterial growth from eye drop containers and the occurrence of serious ocular infections following the use of contaminated solutions have been reported by among others Allen & Mangiaracine (1964), Ayliffe et al (1966), Harte et al (1978), McCulloch (1943), Schmelzer Hervding Contamination of in-use eye drops (1965) and Vaughn (1955). On the other hand, some studies show only a negligible incidence of bacterial growth (Barkman et al 1969;Hugo & Wilson 1970;h u n d et al 1978).…”

Control of Infection in Ophthalmic Surgery

“…But after intraocular operations, sepsis is nearly always very serious; in almost every case there is a real possibility that the eye will be lost. Thus, in a series of 22 infections (Allen & Mangiaracine 1964), evisceration of the eye was necessary in 11 and useful vision was lost in a further 7; in the Birmingham outbreak 15 infections led to the loss of 6 eyes (Ayliffe et al 1966).…”

Alcaligenes xylosoxidans Endophthalmitis Following Phacoemulsification and Intraocular Lens Implantation

“…Several phenotypical methods have been employed in previous studies to identify similarities between bacterial infections, including antimicrobial susceptibility profiles 12,13 or phage, pyocin, and serological typing. 11 Cruciani et al were the first to use genotyping (pulsefield gel electrophoresis) as a means of correlating samples of three strains of P. aeruginosa taken from (1) patients with endophthalmitis following cataract surgery who had been operated on during different days and (2) phacoemulsifier internal tubing. 6 Previous pulsed-field gel electrophoresis tests for Alcaligenes used XbaI, SpeI, or DraI as restriction endonucleases.…”

“…Several reports of clustered endophthalmitis outbreaks following cataract surgery have been published, including series of patients who were operated on during the same day and infected by different bacteria 4 and series of patients operated on during different days and infected by the same bacteria. 6 The most frequently cited bacterium in these studies has been P. aeruginosa, 3,4,6,7,[11][12][13]15 but other bacteria such as Staphylococcus, 4 Acremonium kiliense, 8 and Empedobacter brevis 5 are regularly incriminated. To date, our series is the first to report an endophthalmitis series involving Alcaligenes.…”

Bacterial Contamination of Drops and Dropper Tips of In‐use Multidose Eye Drop Bottles

“…Conflicting views have been presented regarding the frequency and importance of microbial contamination of eye drops. Thus bacterial growth from eye drop containers and the occurrence of serious ocular infections following the use of contaminated solutions have been reported by among others Allen & Mangiaracine (1964), Ayliffe et al (1966), Harte et al (1978), McCulloch (1943), Schmelzer Hervding Contamination of in-use eye drops (1965) and Vaughn (1955). On the other hand, some studies show only a negligible incidence of bacterial growth (Barkman et al 1969;Hugo & Wilson 1970;h u n d et al 1978).…”

Control of Infection in Ophthalmic Surgery

“…But after intraocular operations, sepsis is nearly always very serious; in almost every case there is a real possibility that the eye will be lost. Thus, in a series of 22 infections (Allen & Mangiaracine 1964), evisceration of the eye was necessary in 11 and useful vision was lost in a further 7; in the Birmingham outbreak 15 infections led to the loss of 6 eyes (Ayliffe et al 1966).…”

Alcaligenes xylosoxidans Endophthalmitis Following Phacoemulsification and Intraocular Lens Implantation

“…Several phenotypical methods have been employed in previous studies to identify similarities between bacterial infections, including antimicrobial susceptibility profiles 12,13 or phage, pyocin, and serological typing. 11 Cruciani et al were the first to use genotyping (pulsefield gel electrophoresis) as a means of correlating samples of three strains of P. aeruginosa taken from (1) patients with endophthalmitis following cataract surgery who had been operated on during different days and (2) phacoemulsifier internal tubing. 6 Previous pulsed-field gel electrophoresis tests for Alcaligenes used XbaI, SpeI, or DraI as restriction endonucleases.…”

“…Several reports of clustered endophthalmitis outbreaks following cataract surgery have been published, including series of patients who were operated on during the same day and infected by different bacteria 4 and series of patients operated on during different days and infected by the same bacteria. 6 The most frequently cited bacterium in these studies has been P. aeruginosa, 3,4,6,7,[11][12][13]15 but other bacteria such as Staphylococcus, 4 Acremonium kiliense, 8 and Empedobacter brevis 5 are regularly incriminated. To date, our series is the first to report an endophthalmitis series involving Alcaligenes.…”

Bacterial Contamination of Drops and Dropper Tips of In‐use Multidose Eye Drop Bottles

“…Conflicting views have been presented regarding the frequency and importance of microbial contamination of eye drops. Thus bacterial growth from eye drop containers and the occurrence of serious ocular infections following the use of contaminated solutions have been reported by among others Allen & Mangiaracine (1964), Ayliffe et al (1966), Harte et al (1978), McCulloch (1943), Schmelzer Hervding Contamination of in-use eye drops (1965) and Vaughn (1955). On the other hand, some studies show only a negligible incidence of bacterial growth (Barkman et al 1969;Hugo & Wilson 1970;h u n d et al 1978).…”