Postoperative Complications in Patients With Obstructive Sleep Apnea

Obstructive Sleep Apnea and Oxygen Therapy: A Systematic Review of the Literature and Meta-Analysis

“…57,58 A recent cohort study showed that oxygen desaturation with SpO 2 < 90% was the most common postoperative complication in patients with OSA. 59 These hypoxemic episodes have been shown to have serious consequences, including poor wound healing, cardiac arrhythmias, and delirium. 60,61 The use of supplemental oxygen in the perioperative period has been shown to reduce nausea and vomiting and hospital length of stay, and to improve wound healing.…”

Perioperative Complications in Obstructive Sleep Apnea Patients

“…With two exceptions [22,102], studies reporting on postoperative respiratory failure have found an association between a diagnosis of OSA and higher rates of this complication (OR 1.6-4.3, all statistically significant). The studies reporting an association have used PSG confirmation [104,105] or ICD coding [101,103•] to define OSA, whereas one of the studies that did not find an association used a screening questionnaire to define low and high risk for OSA populations [22]. The other study not finding an association with respiratory failure and an ICD code for OSA noted much higher rates of reintubation (OR 4.4) and CPAP/noninvasive ventilation use (OR 14.1), but not respiratory failure, which suggests potential methodological issues affecting the analysis [102].…”

“…A variety of methodologies were used and a wide spectrum of surgical procedures were evaluated in these analyses. Two studies reporting specifically on postoperative myocardial infarction also failed to find an association with a diagnosis of OSA [25,104].…”

Obstructive Sleep Apnea: A Risk Factor of Cardiac Valve Replacement Surgery

“…Our selection of postoperative adverse outcomes was based on some studies. 6,7 We set up six adverse outcomes at beginning of the study: ICU length of stay ≥ 25 h, mechanical ventilation ≥ 20 h, pacemaker use, cardiopulmonary bypass ≥ 110 min, first dose of dopamine in ICU ≥ 3 μg/kg·min and first dose of dobutamine in ICU ≥ 3 μg/kg·min. However, because of the suggestions from reviewers and editors as well as the following reasons: 1) cardiopulmonary bypass ≥ 110 min was more associated with the complex of cardiac surgery itself rather than perioperative risks; 2) both first dose of dopamine in ICU ≥ 3 µg/kg·min and first dose of dobutamine in ICU ≥ 3 µg/kg·min were more closely related to preoperative cardiac function and bleeding amount during surgery rather than perioperative risks, the adverse events of cardiopulmonary bypass ≥ 110 min, first dose of dopamine in ICU ≥ 3 μg/ kg·min and first dose of dobutamine in ICU ≥ 3 μg/kg·min were deleted.…”

“…Other postoperative adverse events such as reintubation, infection, pneumonia, myocardial infarction, 4,6,[8][9][10] were not included in our original protocol and failed to be recorded in our study as well. This limitation will push us to pursue more proper observation in our further study in the future.…”