Postoperative Complications After Primary Adult Optical Penetrating Keratoplasty: Prevalence and Impact on Graft Survival

Wagoner, Michael D.; Ba-Abbad, Rola; Al-Mohaimeed, Mansour; Al-Swailem, Samar A; Zimmerman, M. Bridget

doi:10.1097/ico.0b013e31818d3aef

Cited by 65 publications

(44 citation statements)

References 79 publications

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“…For nearly half a century, penetrating keratoplasty (PKP) has been the surgical treatment of choice for visual rehabilitation of keratoconus (KC) [1][2][3][4][5][6][7][8][9]. Recently, deep anterior lamellar keratoplasty (DALK) has been introduced as an alternative to PKP.…”

Section: Introductionmentioning

confidence: 99%

Penetrating keratoplasty versus deep anterior lamellar keratoplasty for the treatment of keratoconus

et al. 2010

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Section: Introductionmentioning

confidence: 99%

Penetrating keratoplasty versus deep anterior lamellar keratoplasty for the treatment of keratoconus

et al. 2010

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“…The results further extend the outcome of previous studies that reported the occurrence of one or more complications is associated with an increased risk of graft failure, whereas specific types of complications were not related to risk for graft failure. 24 Some of the complications noted in the present study could be considered less severe than others, such as Desçement's folds and endothelial pigmentation. Excluding these from the overall complications did not affect substantially the results of the analyses.…”

Section: Discussionmentioning

confidence: 89%

The corneal endothelium after keratoplasty for keratoconus

Jonuscheit

Doughty

Ramaesh

2013

Clinical and Experimental Optometry

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Background:The aim was to assess the corneal endothelium, post-operative visual outcome and complications following keratoplasty for keratoconus. Methods: Seventy-six corneal grafts (57 per cent penetrating keratoplasties and 43 per cent deep anterior lamellar keratoplasties) were assessed as part of routine follow-up at the Ophthalmology Department at Gartnavel General Hospital in Glasgow. Routine ophthalmic assessment included visual acuity, slitlamp biomicroscopy and scanning slit confocal microscopy of the central cornea. Case records were reviewed and demographic, surgical and post-operative data retrieved. Linear and logistic regression models were used to determine associations between endothelial cell density, visual acuity and post-operative complications. Kaplan-Meier analysis was used to estimate the probability for grafts to retain more than 700 endothelial cells per mm 2 and to have 0.3 logMAR or better vision. Odds ratios were calculated to assess the risk for low cell counts and poor visual outcome. Results: The mean and standard deviation of the endothelial cell count was predictably higher in lamellar (2033 Ϯ 643 cells per mm

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“…However, one of the most common causes of rejection is associated with endothelial failure surgical technique, which represents a substantial risk to the probability of graft survival, especially if not recognized and treated in time [4,5].…”

Section: Introductionmentioning

confidence: 99%

Lamellar keratoplasty in a referral center in northeastern Brazil

Dantas

Silva

et al. 2016

Int Arch Med

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Objective: To clinically characterize some cases of lamellar keratoplasty performed in a referral center of Rio Grande do Norte state.Methods: This is a cross-sectional, retrospective study, which is the review of the medical records of 18 patients who underwent keratoplasty of lamellar type in a referral service in Natal/RN.Results: it was found that of 18 patients who underwent keratoplasty, 55.56% were male, being all patients with deep anterior lamellar. Regarding the age group, 66.67% were thirty years old or less. The corneal vascularization of tissue was a factor receptor absent in 77.78% of cases. The main indication for lamellar keratoplasty were keratoconus (66.66%). Of the cases in which transplantation was done with urgency, ocular diagnoses were not infectious ulcerative keratitis (50%), corneal degeneration (25%) and leukoma (25%). Conclusion:it is cocluded that the main indicator condition for lamellar keratoplasty was keratoconus. Patients who underwent the procedure were 30 years old or less, with minimum level of corneal vascularization and absence of glaucoma. Furthermore, the surgical technique predominantly used for lamellar transplantation was the deep lamellar keratoplasty due to its advantages over penetrating keratoplasty.

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Postoperative Complications After Primary Adult Optical Penetrating Keratoplasty: Prevalence and Impact on Graft Survival

Abstract: The prevalence of post-PKP complications and their impact on graft survival vary significantly among surgical indications for primary adult optical PKP.

Cited by 65 publications

References 79 publications

Penetrating keratoplasty versus deep anterior lamellar keratoplasty for the treatment of keratoconus

Penetrating keratoplasty versus deep anterior lamellar keratoplasty for the treatment of keratoconus

The corneal endothelium after keratoplasty for keratoconus

Lamellar keratoplasty in a referral center in northeastern Brazil

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