Postoperative choroidal vascularity index after the management of macula-off rhegmatogenous retinal detachment

Abstract

Background Rhegmatogenous retinal detachment (RRD) is a vision-threatening condition that can be treated with various surgical approaches. The role of scleral buckling remains controversial because of its potential long-term deleterious effects on choroidal vascular perfusion and the limited knowledge of this entity. Methods A total of 135 eyes were retrospectively selected, including 115 with surgically resolved RRD and 20 healthy control eyes. Of the surgically treated eyes, 64 underwent vitrectomy alone, while 51 underwent scleral buckling combined with vitrectomy. Best-corrected visual acuity (BCVA) was evaluated along with the choroidal vascularity index (CVI) as a metric for the state of the choroidal vasculature. BCVA was compared before and after surgery, and the postoperative BCVA was analyzed with the CVI using correlation and multivariate regression analyses. Results The preoperative BCVA of the RRD eyes was significantly worse than that of the control eyes, and significantly improved after surgery. However, the long-term postsurgical BCVA was still inferior to that of the control eyes. No significant differences in visual function were found between the two surgical groups. The average CVI was 57.35% in the control eyes, 63.76% in the eyes that underwent vitrectomy, and 53.37% in buckled eyes. The differences in CVI were significant among the three groups. Among the surgical patients, negative Pearson’s correlations were found between CVI and postoperative BCVA (expressed in logMAR). A multivariate linear regression model containing four parameters revealed that CVI was the only variable with a significant influence on postoperative BCVA, while the length of time with a detached macula did not have an effect. Conclusions RRD surgery drastically restored vision, but the effect of RRD lingered, as postsurgical visual acuity remained inferior to that of the control eyes. The CVI varied between the treatment groups, likely due to both disease pathology and the impact of the surgery. The correlation between CVI and BCVA indicates the important role that the choroidal vasculature plays in visual function.

Postoperative Choroidal Vascular Biomarkers in Eyes with Rhegmatogenous Retinal Detachment-Related Giant Retinal Tears

“…The protocol study method for binarization is shown in Fig. 1 and has been validated in a previous publication [ 38 ]. The CFA was obtained by automated binarization and segmentation of the choriocapillaris subfoveal plexus slabs using the RTVue XR OCT Avanti with AngioVue Software (OptoVue Inc., Fremont, CA, USA) and automatically calculated from a 3.142 mm 2 evaluation area (Fig.…”

Correction: Postoperative choroidal vascularity index after the management of macula-off rhegmatogenous retinal detachment

“…1186/ s40942-023-00454-z. *Correspondence: Miguel A. Quiroz-Reyes drquiroz@prodigy.net.mx 1 The retinal break was treated with an argon endolaser, and fluid-gas exchange was performed using a non-expandable 15% perfluoropropane gas mixture at the end of the procedure. After 8 months of serial follow-up, the eye had a BCVA of 20/40 (logMAR) at the patient's last visit.…”

“…Following publication of the original article [ 1 ], the authors identified an error in their article. Figure 3 was erroneously omitted from the published article.…”